Computers have transformed nearly every aspect of modern life, and research in the biological sciences is no exception. In fact, computers have spawned a new field of Biology called Bioinformatics. Bioinformatics is the science of creating, managing, and mining biological information from sources as diverse as medical records, images and sequence data. My own laboratory is particularly interested in sequence data. Usually DNA consists of just 4 nucleotides, denoted with the letters A, T, G, & C. The human genome sequence, for example, is some 3 billion characters long. At 500 words per page, that¿s a book 6,000,000 pages long. Manipulating, managing and deciphering a sequence of this size are largely computer-based endeavors; and creating tools to aid these ends is the central focus of research in my laboratory.
Lab Website: www.yandell-lab.org