leppert

Providing researchers throughout the worldwide genomic community with access to genetic markers and techniques for rapid, large-scale genotyping efforts will contribute to rapid advances in the identification of genes and treatments associated with diseases in humans. In turn, these discoveries will lead to new preventions for inherited disorders.

An aim of our research group is to develop new and improved techniques for identifying genetic variations that confer predispositions to human disorders and traits. The ascertainment of families in which such variant genes are segregating is an important first step toward localizing the disease-related genes on specific chromosomes. The genealogical resources available at the University of Utah have enabled researchers in human genetics to identify extended families who can contribute such information. Localization of a variant gene predisposing to a disease is accomplished by finding a marker allele that is inherited along with the disease phenotype. However, as many common diseases in humans are complex in their phenotypic expression, and as several genes may be involved, often large numbers of related individuals have to be genotyped at many marker loci. This requirement has led our group to adapt technologies evolving from DNA sequence research to the problem of large-scale and rapid genotyping. We are using this genetic approach, coupled with positional cloning, to understand inherited forms of epilepsy, particularly a specific type in which intermittent seizures appear at birth and cease spontaneously within six months, and to understand inherited forms of macular degeneration, a common form of retinal eye disease.

Unprecedented efforts aimed at extensive phenotyping of Utah families as part of the Utah Genetic Reference Project have yielded successful progress toward identifying the genetic loci responsible for quantitative traits such as phenylthiocarbamide sensitivity and variation in levels of lymphocyte subpopulations. These same families were utilized for the construction of the haplotype map for the International HapMap Project, which will readily facilitate the discovery of allelic variants responsible for common diseases.

Li Y, Liao W, Cargill M, Chang M, Matsunami N, Feng BJ, Poon A, Callis-Duffin KP, Catanese JJ, Bowcock AM, Leppert MF, Kwok PY, Krueger GG, Begovich AB. Carriers of rare missense variants in IFiH1 are protected from psoriasis. J Invest Dermatol. 2010 Jul 29. PMID20668468

Neklason DW, Tuohy TM, Stevens J, Otterud B, Baird L, Kerber RA, Samowitz WS, Kuwada SK, Leppert MF, Burt RW. Colorectal adenomas and cancer link to chromosome 13q22.1-13q31.3 in a family with excess colorectal cancer. J Med Genet. 2010 Jun 3. PMID20522424

McClay JL, Adkins DE, Isern NG, O’Connell TM, Wooten JB, Zedler BK, Dasika MS, Webb BT, Webb-Robertson BJ, Pounds JG, Murrelle EL, Leppert MF, van den Oord EJ. (1)H Nuclear magnetic resonance metabolomics analysis identifies novel urinary biomarkers for lung function. J Proteome Res. 2010 May 3. PMID20408573

Watkins WS, Rohrwasser A, Peiffer A, Leppert MF, Lalouel J-M, Jorde LB. AGT genetic variation, plasma AGT, and blood pressure: An analysis of the Utah Genetic Reference Project Pedigrees. Am J Hypertens. 2010 Apr 22. PMID20414195

Devanarayan V, Scholand MB, Hoidal J, Leppert MF, Crackower MA, O’Neill GP, Gervais FG. Identification of distinct plasma biomarker signatures in patients with rapid and slow declining forms of COPD. COPD. 2010. Feb;7(1):51-8. PMID20214463

Bleakley M, Otterud BE, Richardt JL, Mollerup AD, Hudecek M, Nishida T, Chaney CN, Warren EH, Leppert MF, Riddell SR. Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naïve CD8+ Tcells. Blood. 2010. Mar 4. PMID20203263

Kumanovics A, Wittwer CT, Pryor RJ, Augustine NH, Leppert MF, Carey JC, Ochs HD, Wedgwood RJ, Faville RJ Jr, Quie PG, Hill HR. Rapid molecular analysis of the STAT3 gene in job syndrome of hyper-IgE and recurrent infectious diseases. J Mol Diagn. 2010. Mar;12(2):213-9. PMID20093388

Bleyl SB, Saijoh Y, Bax NA, Gittenberger-de Groot AC, Wisse LJ, Chapman SC, Hunter J, Shiratori H, Hamada H, Yamada S, Shiota K, Klewer SE, Leppert MF, Schoenwolf GC. Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organisms. Hum Mol Genet. 2010. Apr 1;19(7):1286-307 PMID20071345

North KE, Franceschini N, Avery CL, Baird L, Graff M, Leppert M, Chung JH, Zhang J, Hanis C, Boerwinkle E, Volcik KA, Grove ML, Mosley TH, Gu C, Heiss G, Pankow JS, Couper DJ, Ballantyne CM, Linda Kao WH, Weder AB, Cooper RS, Ehret GB, O’Connor AA, Chakravarti A, Hunt SC. Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations. Acta Diabetol. 2009. Oct 24. PMID19855918

Knight S, Coon H, Johnson M, Leppert MF, Camp NJ, McMahon WM. Linkage analysis of Tourette syndrome in a large Utah pedigree. Tourette Syndrome Association International Consortium for Genetics. Am J Med Genet B Neuropsychiatr Genet. 2010. Mar 5;153B(2):656-62 PMID19777563

Singh NA, Pappas C, Dahle EJ, Claes LRF, Pruess TH, DeJonghe P, Thompson J, Dixon M, Gurnett C, Peiffer A, White HS, Filloux F, Leppert MF. A role of SCN9A in human epilepsies, as a cause of febrile seizures and as a potential modifier of Dravet Syndrome. PLoS Genetics. 2009. Sep;5(9) PMID19763161

Allen-Brady K, Robison R, Cannon D, Varvil T, Villalobos M, Pingree C, Leppert MF, Miller J, McMahon WM, Coon H. Genome-wide linkage in Utah autism pedigrees. Mol Psychiatry 2009. May 19. PMID19455147

Baker TB, Weiss RB, Bolt D, von Niederhausern A, Fiore MC, Dunn DM, Piper ME, Matsunami N, Smith SS, Coon H, McMahon WM, Scholand MB, Singh N, Hoidal JR, Kim SY, Leppert MF, Cannon DS. Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes. Nicotine Tob Res. 2009. Jul;11(7):785-96. PMID19436041

Otto JF, Singh NA, Dahle EJ, Leppert MF, Pappas CM, Pruess TH, Wilcox KS, White HS. Electroconvulsive seizure thresholds and kindling acquisition rates are altered in mouse models of human Kcnq2 and Kcnq3 mutations for benign familial neonatal convulsions. Epilepsia. 2009. ** 1-8 PMID19453707

Freedman BI, Kopp JB, Winkler CA, Nelson GW, Rao DC, Eckfeldt JH, Leppert MF, Hichk PJ, Divers J, Langefeld CD, Hunt SC. Polymorphisms in the nonmuscle myosin heavy chain 9 gene (MYH9) are associated with albuminuria in hypertensive African Americans: The HyperGEN Study. Am J Nephrol. 2009. Jan 20;29(6):626-632. PMID19153477

Boutin M, Berthelette C, Gervais FG, Scholand MB, Hoidal J, Leppert MF, Bateman KP, Thibault P. High-sensitivity nanoLC-MS/MS analysis of urinary desmosine and isodesmosine. Anal Chem. 2009. [Epub ahead of print]. PMID19178285

Franceschini N, North KE, Arnett D, Pankow JS, chung JH, Baird L, Leppert MF, Eckfeldt JH, Boerwinkle E, Gu CC, Lewis CE, Myers RH, Turner ST, Weder A, Kao WH, Mosley TH, Chakravarti A, Kramer H, Zhang J, Hunt SC. The association of cell cycle checkpoint 2 variants and kidney function: Findings of the family blood pressure program and the atherosclerosis risk in communities study. Am J Hypertens. 2009. Mar 5 [Epub ahead of print]. PMID19265784

Butterfield RJ, Ramachandran D, Hasstedt SJ, Otterud BE, Leppert MF, Swoboda KJ, Flanigan KM. A novel form of juvenile recessive ALS maps to loci on 7p25 and 21q22. Neuromuscul Disord. 2009. 19:279-287. PMID19318250

Li Y, Liao W, Chang M, Schrodi SJ, Bui N, Catanese JJ, Poon A, Matsunami N, Callis-Duffin KP, Leppert MF, Bowcock AM, Kwok PY, Krueger GG, Begovich AB. Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22. J Invest Dermatol. 2009. Mar;129(3):629-34. PMID18923449

Spaapen RM, Lokhorst HM, van den Oudenalder K, Otterud BE, Dolstra H, Leppert MF, Minnema MC, Bloem AC, Mutis T. Toward targeting B cell cancers with CD4+ CTLs: Identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis. J Exp Med. 2008. Nov 24;205(12):2863-72. PMID19001137

Neklason DW, Thorpe BL, Ferrandez A, Tumbapura A, Boucher K, Garibotti G, Kerber RA, Solomon CH, Samowitz WS, Fang JC, Mineau GP, Leppert MF, Burt RW, Kuwada SK. Colonic adenoma risk in familial colorectal cancer—a study of six extended kindreds. Am J Gastroenterol. 2008. Oct;103(10):2577-84. PMID18671820

Weiss RB, Baker TB, Cannon DS, von Niederhausern A, Dunn DM, Matsunami N, Singh NA, Baird L, Coon H, McMahon WM, Piper ME, Fiore MC, Scholand MB, Connett JE, Kanner RE, Gahring LC, Rogers SW, Hoidal JR, Leppert MF. A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. PLoS Genetics. 2008. 4(7):e1000125. PMID18618000

Singh NA, Otto JF, Dahle EJ, Pappas C, Leslie JD, Vilaythong A, Noebels JL, White HS, Wilcox KS, Leppert MF. Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization. J Physiol, 2008 586(14):3405-3423. PMID18483067

Prescott SM, Lalouel JM, Leppert M. From linkage maps to quantitative trait loci: The history and science of the Utah Genetics Reference Project. Annu Rev Genomics Hum Genet. 2008 9: 347-58.

Hobbs MR, Jones BB, Otterud BE, Leppert M, Kriesel JD. Identification of a herpes simplex labialis susceptibility region on human chromosome 21. J Infect Dis. 2008 197(3):340-6.

Garcia VE, Chang M, Brandon R, Li Y, Matsunami N, Callis-Duffin KP, Civello D, Rowland CM, Bui N, Catanese JJ, Krueger GG, Leppert MF, Begovich AB, Schrodi SJ. Detailed genetic characterization of the interleukin-23 receptor in psoriasis. Genes Immun. 2008. Sep;9(6):546-55. PMID18650833

Renner ED, Rylaarsdam S, Anover-Sombke S, Rack AL, Reichenbach J, Carey JC, Zhu Q, Jansson AF, Barboza J, Schimke LF, Leppert MF, Getz MM, Seger RA, Hill HR, Belohradsky BH, Torgerson TR, Ochs HD. Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-lgE syndrome. J Allergy Clin Immunol. 2008. Jul;122(1):181-7. PMID18602572

Li Y, Chang M, Schrodi SJ, Callis-Duffin KP, Matsunami N, Civello D, Bui N, Catanese JJ, Leppert MF, Krueger GG, Begovich AB. The 5q31 variants associated with psoriasis and Crohn’s disease are distinct. Hum Mol Genet. 2008. Oct 1;17(19):2978-85. PMID18614543

Arrington CB, Sower CT, Chuckwuk N, Stevens J, Leppert MF, Yetman AT, Bowles NE. Absence of TGFBR1 and TGFBR2 mutations in patients with bicuspid aortic valve and aortic dilation. Am J Cardiol. 2008. Sep 1;102(5):629-31. PMID18721526

Bjornsson HT, Sigurdsson MI, Fallin MD, Irizarry RA, Aspelund T, Cui H, Yu W, Rongione MA, Ekstrom TJ, Harris TB, Launer LJ, Eiriksdottir G, Leppert MF, Sapienza C, Gudnason V, Feinbert AP. Intra-individual change over time in DNA methylation with familial clustering. JAMA. 2008. 299(24):2877-2883. PMID18577732

Rainier S, Bui M, Mark E, Thomas D, Tokarz D, Ming L, Delaney C, Richardson RJ, Albers JW, Matsunami N, Stevens J, Coon H, Leppert M, Fink JK. Neuropathy target esterase gene mutations cause motor neuron disease. Am J Hum Genet. 2008. 82:780-785.

Neklason DW, Stevens J, Boucher KM, Kerber RA, Matsunami N, Barlow J, Mineau G, Leppert MF, Burt RW. American founder mutation for attenuated familial adenomatous polyposis. Clin Gastroenterol Hepatol. 2008..Jan;6(1):46-52. PMId18063416

Chang, M, Li Y, Yan C, Callis-Duffin KP, Matsunami N, Garcia VE, Cargill M, Civello D, Bui N, Catanese JJ, Leppert MF, Krueger GG, Begovich AB, Schrodi SJ. Variants in the 5q31 cytokine gene cluster are associated with psoriasis. Genes Immun. 2008. 9(2):176-181. PMID18075513

Sabeti PC, Varilly P, Fry B, Lohmueller J, Hostetter E, Cotsapas C, Xie X, Byrne EH, McCarroll SA, Gaudet R, Schaffner SF Lander ES; International HapMap Consortium et al. Genome-wide detection and characterization of positive selection in human populations. Nature. 2007 Oct 18;449(7164):913-18. PMID17943131

International HapMap Consortium et al. A second generation human haplotype map of over 3.1 million SNPs. Nature. 2007 Oct 18;449(7164):851-61. PMID17943122

Rotimi C, Leppert M, Matsuda I, Zeng C, Zhang H, Adebamowo C, Ajayi I, Aniagwu T, Dixon M, Fukushima Y, Macer D, Marshall P, Nkwodimmah C, Peiffer A, Royal C, Suda E, Zhao H, Wang VO, McEwen J; The International HapMap Consortium. Community engagement and informed consent in the International HapMap project. Community Genet. 2007 10(3):186-98.

Cannon DS, Tiffany ST, Coon H, Scholand MB, McMahon WM, Leppert MF. The PHQ-9 as a brief assessment of lifetime major depression. Psychol Assess. 2007 Jun;19(2):247-51. PMID17563207

Cargill M, Schrodi SJ, Chang M, Garcia VE, Brandon R, Callis KP, Matsunami N, Ardlie KG, Civello D, Catanese JJ, Leong DU, Panko JM, McAllister LB, Hansen CB, Papenfuss J, Prescott SM, White TJ, Leppert MF, Krueger GG, Begovich AB. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet. 2007 Feb;80(2):273-90.

Tourette Syndrome Association International Consortium for Genetics. Genome scan for Tourette Disorder in affected-sibling-pair and multigenerational families. Am J Hum Genet. 2007 80(2):265-272.

Zimprich F, Ronen GM, Stogmann W, Baumgartner C, Stogmann E, Rett B, Pappas C, Leppert M, Singh N, Anderson VE. Andreas Rett and benign familial neonatal convulsions revisited. Neurology. 2006 Sep 12;67(5):864-6.

Hubbard AF, Askew EW, Singh N, Leppert M, Bernstein PS. Association of adipose and red blood cell lipids with severity of dominant Stargardt mascular dystroph (STGD3) secondary to an ELOVL4 mutation. Arch Ophthalmol. 2006 124(2):257-63.

Bleyl SB, Botto LD, Carey JC, Young LT, Bamshad MJ, Leppert MF, Ward K. Analysis of a Scottish founder effect narrows the TAPVR-1 gene interval to chromosome 4q12. Am J Med Genet A. 2006 Nov 1;140(21):2368-73.

de Rijke B, van Horssen-Zoetbrood A, Beekman JM, Otterud B, Maas F, Woestenenk R, Kester M, Leppert M, Schattenberg AV, de Witte T, van de Wiel-van Kemenade E, Dolstra H. A grameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia. J Clin Invest. 2005 115:3506-3516.

Coon H, Matsunami N, Stevens J, Miller J, Pingree C, Camp NJ, Thomas A, Krasny L, Lainhart J, Leppert MF, McMahon W. Evidence for linkage on chromosome 3q25-27 in a large autism extended pedigree. Hum Hered. 2005 60:220-6.

Wilk JB, Myers RH, Pankow JS, Hunt SC, Leppert MF, Freedman BI, Province MA, Ellison RC. Adrenergic receptor polymorphisms associated with resting heart rate: The HyperGEN Study. Ann Hum Genet. 2005 69:1-9.

Cannon DS, Baker TB, Piper ME, Scholand MB, Lawrence DL, Drayna DT, McMahon WM, Villegas GM, Caton TC, Coon H, Leppert MF. Associations between phenylthiocarbamide gene polymorphisms and cigarette smoking. Nicotine Tob Res. 2005 Dec;7(6):853-58.

Sandovici I, Kassovska-Bratinova S, Loredo-Osti JC, Leppert M, Suarez A., Stewart R, Bautista FD, Schiraldi M, Sapienza C. Interindividual variability and parent of origin DNA methylation differences at specific human Alu elements. Hum Mol Genet. 2005 Aug 1;14(15):2135-43. Epub 2005 Jun 22.

Pankow JS, Dunn DM, Hunt SC, Leppert MF, Miller MB, Rao DC, Heiss G, Oberman A, Lalouel JM, Weiss RB. Further evidence of a quantitative trait locus on chromosome 18 influencing postural change in systolic blood pressure: the Hypertension Genetics Epidemiology Network (HyperGEN) Study. Am J Hypertens. 2005 May;18(5 Pt 1):672-8.

Coon H, Dunn D, Lainhart J, Miller J, Hamil C, Battaglia A, Tancredi R, Leppert MF, Weiss R, McMahon W. Possible association between autism and variants in the brain-expressed tryptophan hydroxylase gene (TPH2). Am J Med Genet B Neuropsychiatr Genet. 2005 May 5;135(1):42-6.

Malhotra A, Cromer K, Leppert MF, Hasstedt SJ. The power to detect genetic linkage for quantitative traits in the Utah CEPH pedigrees. J Hum Genet. 2005 50(2):69-75. Epub 2005 Jan 29.

Jorgenson E, Tang H, Gadde M, Province M, Leppert M, Kardia S, Schork N, Cooper R, Rao DC, Boerwinkle E, Risch N. Ethnicity and human genetic linkage maps. Am J Hum Genet. 2005 Feb;76(2):276-90. Epub 2004 Dec 30.

Tykodi SS, Warren EH, Thompson JA, Riddell SR, Childs RW, Otterud BE, Leppert MF, Storb R, Sandmaier BM. Allogeneic hematopoietic cell transplantation for metastatic renal cell carcinoma after nonmyeloablative conditioning: toxicity, clinical response, and immunological response to minor histocompatibility antigens. Clin Cancer Res. 2004 Dec 1;10(23):7799-811.

Arnett DK, Miller MB, Coon H, Ellison RC, North KE, Province M, Leppert M, Eckfeldt JH. Genome-wide linkage analysis replicates susceptibility locus for fasting plasma triglycerides: NHLBI Family Heart Study. Hum Genet. 2004 Nov;115(6):468-74. Epub 2004 Sep 16.

Sandovici I, Naumova AK, Leppert M, Linares Y, Sapienza C. A longitudinal study of X-inactivation ratio in human females. Hum Genet. 2004 Oct;115(5):387-92. Epub 2004 Aug 28.

Burt RW, Leppert MF, Slattery ML, Samowitz WS, Spirio LN, Kerber RA, Kuwada SK, Neklason DW, Disario JA, Lyon E, Hughes JP, Chey WY, White RL. Genetic testing and phenotype in a large kindred with attenuated familial adenomatous polyposis. Gastroenterology. 2004 Aug;127(2):444-51.

Norman PJ, Cook MA, Carey BS, Carrington CVF, Verity DH, Hameed K, Ramdath DD, Chandanayingyong D, Leppert M, Stephens HAF, Vaughan RW. SNP haplotypes and allele frequencies show evidence for disruptive and balancing selection in the human leukocyte receptor complex. Immunogenetics. 2004 Jul;56(4):225-37. Epub Jun 5.

Berrettini W, Bierut L, Crowley TJ, Cubells JF, Frascella J, Gelernter J, Hewitt JK, Kreek MJ, Lachman H, Leppert M, Li MD, Madden P, Miner C, Pollock JD, Pomerleau O, Rice JP, Rutter JL, Shurtleff D, Swan GE, Tischfield JA, Tsuang M, Uhl GR, Vanyukov M, Volkow ND, Wanke K. Setting priorities for genomic research. Science. 2004 Jun 4;304(5676):1445-7; author reply 1446-7.

Swoboda KJ, Kanavakis E, Xaidara A, Johnson JE, Leppert MF, Schlesinger-Massart MB, Ptacek LJ, Silver K, Youroukos S. Alternating hemiplegia of childhood or familial hemiplegic migraine?: A novel ATP1A2 mutation. Ann Neurol. 2004 Jun;55(6):884-7.

Coon H, Singh N, Dunn D, Eckfeldt JH, Province MA, Hopkins PN, Weiss R, Hunt SC, Leppert MF. TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study. Atherosclerosis. 2004 Jun;174(2):357-62.

Drayna D, Kim UK, Coon H, Jorgenson E, Risch N, Leppert M. A model system for identifying genes underlying complex traits. Cold Spring Harbor Symp Quant Biol. 2003 68:365-71.

Tang W, Miller MB, Rich SS, North KE, Pankow JS, Borecki IB, Myers RH, Hopkins PN, Leppert M, Arnett DK. Linkage analysis of a composite factor for the multiple metabolic syndrome. Diabetes. 2003 Nov 52: 2840-2847.

Tang W, Devereux RB, Kitzman DW, Province MA, Leppert M, Oberman A, Hopkins PN, Arnett DK. The Arg16Gly polymorphism of the beta2-adrenergic receptor and left ventricular systolic function. Am J Hypertens. 2003 16:945-951.

Singh, NA, Westenskow P, Charlier C, Pappas C, Leslie J, Dillon J, The BFNC Physician Consortium, Anderson VE, Sanguinetti MC, Leppert MF. KCNQ2 and KCNQ3 potassium channel genes in benign familial neonatal convulsions: expansion of the functional and mutation spectrum. Brain. 2003 126(12):2726-2737.

Leppert, MF and Singh, NA. Nonsyndromic seizure disorders: Epilepsy and the use of the internet to advance research. Annu Rev Genomics Hum Genet. 2003 Sep 4:437-457.

Malhotra A, Peiffer AP, Ryujin DT, Elsner T, Kanner RE, Leppert MF, Hasstedt SJ. Further evidence for the role of genes on chr2 and chr5 in the inheritance of pulmonary function. Am J Respir Crit Care Med. 2003 Sep 1;168(5):556-61. Epub 2003 Jun 05.

Sandovici I, Leppert M, Hawk PR, Suarez A, Linares Y, Sapienza C. Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions. Hum Mol Genet. 2003 Jul 1;12(13):1569-1578.

Wilk JB, DeStefano AL, Arnett DK, Rich SS, Djousse L, Crapo RO, Leppert MF, Province MA, Cupples LA, Gottlieb DJ, Myers RH. A genome-wide scan of pulmonary function measures in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Respir Crit Care Med. 2003 Jun 1;167(11):1528-33.

Drayna D, Coon H, Kim UK, Elsner T, Cromer K, Otterud B, Baird L, Peiffer AP, Leppert M. Genetic analysis of a complex trait in the Utah Genetic Reference Project: A major locus for PTC taste ability on chromosome 7q and a secondary locus on chromosome 16p. Hum Genet. 2003 May;112(5-6):567-72.

Rao DC, Province MA, Leppert MF, Oberman A, Heiss G, Ellison RC, Arnett DK, Eckfeldt JH, Schwander K, Mockrin SC, Hunt SC. A genome-wide affected sibpair linkage analysis of hypertension: the HyperGEN network. Am J Hypertens. 2003 Feb;16(2):148-50.

Matthay MA, Zimmerman GA, Esmon C, Bhattacharya J, Coller B, Doerschuk CM, Floros J, Gimbrone MA Jr, Hoffman E, Hubmayr RD, Leppert M, Matalon S, Munford R, Parsons P, Slutsky AS, Tracey KJ, Ward P, Gail DB, Harabin AL. Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med. 2003 Apr 1;167(7):1027-35. Review.

Kim UK, Jorgenson E, Coon H, Leppert M, Risch N, Drayna D. Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science. 2003 Feb 21;299(5610):1221-5.

Anderson E, Berkovic S, Dulac O, Gardiner M, Jain S, Laue-Friis M, Lindhout D, Noebels J, Ottman R, Scaramelli A, Serratosa J, Steinlein O, Avanzini G, Bailey-Wilson J, Cardon L, Fischbach R, Gwinn-Hardy K, Leppert M, Ott J, Lindblad-Toh K, Weiss K. ILAE genetics commission conference report: molecular analysis of complex genetic epilepsies. Epilepsia. 2002 Oct;43(10):1262-7.

Dunn DM, Ishigami T, Pankow J, von Niederhausern A, Alder J, Hunt SC, Leppert MF, Lalouel J-M, Weiss RB. Common variant of human NEDD4L activates a cryptic splice site to form a frameshifted transcript. J Hum Genet. 2002 47(12):665-76.

Coon H, Eckfeldt JH, Leppert MF, Myers RH, Arnett DK, Heiss G, Province MA, Hunt SC. A genome-wide screen reveals evidence for a locus on chromosome 11 influencing variation in LDL cholesterol in the NHLBI Family Heart Study. Hum Genet. 2002 Sep;111(3):263-269.

Warren EH, Otterud BE, Linterman RW, Brickner AG, Engelhard VH, Leppert MF, Martin PJ, Riddell SR. Feasibility of using genetic linkage analysis to identify the genes encoding T cell-defined minor histocompatibility antigens. Tissue Antigens. 2002 Apr;59(4):293-303.

Hunt SC, Ellison RC, Atwood LD, Pankow JS, Province MA, Leppert MF. Genome scans for blood pressure and hypertension: the NHLBI Family Heart Study. Hypertension. 2002 Jul;40(1):1-6.

Samowitz WS, Curtin K, Ma K-N, Edwards S, Schaffer D, Leppert MF, Slattery ML. Prognostic significance of p53 mutations in colon cancer at the population level. Int J Cancer. 2002 Jun 1;99(4):597-602.

Hall MA, Norman PJ, Thiel B, Tiwari H, Peiffer A, Vaughan RW, Prescott S, Leppert M, Schork NJ, Lanchbury JS. Quantitative trait loci on chromosomes 1, 2, 3, 4, 8, 9, 11, 12, and 18 control variation in levels of T and B lymphocyte subpopulations. Am J Hum Genet. 2002 May;70(5):1172-1182.

Bernstein PS, Leppert M, Singh N, Dean M, Lewis RA, Lupski JR, Allikmets R, Seddon JM. Genotype–phenotype analysis of ABCR variants in macular degeneration probands and siblings. Invest Ophthalmol Vis Sci. 2002 Feb;43(2):466-473.

FBPP Investigators. Multi-center genetic study of hypertension: The family blood pressure program (FBPP). Hypertension. 2002 Jan;39(1):3-9.

Swoboda KJ, Soong BW, McKenna C, Brunt ER, Litt M, Bale JF Jr, Ashizawa T, Bennet LB, Bowcock AM, Roach ES, Gerson D, Matsuura T, Heydemann PT, Nespeca MP, Jankovic J, Leppert MF, Ptacek LJ. Paroxysmal dyskinesia and infantile convulsions. Clinical and linkage studies. Neurology. 2001 Dec;57(11 Suppl 4):S42-8.

Samowitz WS, Curtin K, Leppert MF, Slattery ML. Uncommon TGFBRI allele is not associated with increased susceptibility to colon cancer. Genes Chromosomes Cancer. 2001 Dec;32(4):381-3.

Coon H, Leppert MF, Eckfeldt JH, Oberman A, Myers RH, Peacock JM, Province MA, Hopkins PN, Heiss G. Genome-wide linkage analysis of lipids in the hypertension genetic epidemiology network (HyperGEN) blood pressure study. Arterioscler Thromb Vasc Biol. 2001 Dec;21(12):1969-76.

Bernstein PS, Tammur J, Singh N, Hutchinson A, Dixon M, Pappas CM, Zabriskie NA, Zhang K, Petrukhin K, Leppert M, Allikmets R. Diverse macular dystrophy phenotype caused by a novel complex mutation in the ELOVL4 gene. Invest Ophthalmol Vis Sci. 2001 Dec;42(13):3331-36.

Feitosa MF, Borecki IB, Rich SS, Arnett DK, Sholinsky P, Myers RH, Leppert M, Province MA. Quantitative-trait loci influencing body mass index reside on chromosomes 7 and 13: The National Heart, Lung, and Blood Institute Family Heart Study. Am J Hum Genet. 2002 Jan;70(1):72-82.

Samowitz WS, Curtin K, Lin HH, Robertson MA, Schaffer D, Nichols M, Gruenthal K, Leppert MF, Slattery ML. The colon cancer burden of genetically defined hereditary nonpolyposis colon cancer. Gastroenterology. 2001 Oct;121(4):830-838.

Samowitz WS, Curtin K, Ma K-N, Schaffer D, Coleman LW, Leppert M, Slattery ML. Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level. Cancer Epidemiol Biomarkers Prev. 2001 Sep;10(9):917-23.

Flanigan KM, Coffeen CM, Sexton L, Stauffer D, Brunner S, Leppert MF. Genetic characterization of a large, historically significant Utah kindred with facioscapulohumeral dystrophy. Neuromuscular Disord. 2001 Sep;11(6-7):525-29.

Samowitz WS, Holden JA, Curtin K, Edwards SL, Walker AR, Lin HA, Robertson MA, Nichols MF, Gruenthal KM, Lynch BJ, Leppert MF, Slattery ML. Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer. Am J Pathol. 2001 Apr;158(4):1517-24.

Slattery ML, Samowitz W, Ballard L, Schaffer D, Leppert M, and Potter JD. A molecular variant of the APC gene at codon 1822: its association with diet, lifestyle, and risk of colon cancer. Cancer Res. 2001 Feb 1;61(3):1000-4.

Scott BT, Bovill EG, Callas PW, Hasstedt SJ, Leppert MF, Valliere JE, Varvil TS, Long GL. Genetic screening of candidate genes for a prothrombotic interaction with type I protein C deficiency in a large kindred. Thromb Haemost. 2001 Jan;85(1):82-7.

Slattery ML, Curtin K, Anderson K, Ma K-N, Edwards S, Leppert M, Potter J, Schaffer D, Samowitz WS. Associations between dietary intake and Ki-ras mutations in colon tumors: a population-based study. Cancer Res. 2000 Dec 15;60(24):6935-41.

Samowitz WS, Curtin K, Schaffer D, Robertson M, Leppert M, Slattery ML. Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study. Cancer Epidemiol Biomarkers Prev. 2000 Nov;9(11):1193-7.

Slattery ML, Curtin K, Anderson K, Ma K-N, Ballard L, Edwards S, Schaffer D, Potter J, Leppert M, Samowitz WS. Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors. J Natl Cancer Inst. 2000 Nov 15;92(22):1831-36.

Coon H, Myers RH, Borecki IB, Arnett DK, Hunt SC, Province MA, Djousse L, Leppert MF. Replication of linkage of familial combined hyperlipidemia to chromosome 1q with additional heterogeneous effect of apolipoprotein A-I/C-III/A-IV locus: The NHLBI Family Heart Study. Arterioscler Thromb Vasc Biol. 2000 Oct;20(10):2275-80.

Williams RR, Rao DC, Ellison RC, Arnett DK, Heiss G, Oberman A, Eckfeldt JH, Leppert MF, Province MA, Mockrin SC, Hunt SC. NHLBI Family Blood Program: Methodology and recruitment in the HyperGEN Network. Ann Epidemiol. 2000 Aug;10(6):389-400.

Leppert M. Novel K+ channel genes in benign familial neonatal convulsions. Epilepsia. 2000 Aug;41(8): 1066-7.

Province MA, Boerwinkle E, Chakravarti A, Cooper R, Fornage M, Leppert M, Risch N, Ranade K. Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. J Hypertens. 2000 Jul;18(7):867-76.

Swoboda KJ, Soong B-W, McKenna C, Brunt ERP, Litt M, Bale JF Jr, Ashizawa T, Bennett LB, Bowcock AM, Roach ES, Gerson D, Matsuura T, Heydemann PT, Nespeca MP, Jankovic J, Leppert M, Ptacek LJ. Paroxysmal kinesigenic dyskinesia and infantile convulsions: clinical and linkage studies. Neurology. 2000 Jul 25;55(2):224-30.

Danziger RS, Pappas C, Barnitz C, Varvil T, Hunt SC, Leppert MF. Evaluation of heterodimeric guanylyl cyclase genes as candidates for human hypertension. J Hypertens. 2000 18:263-66.

Hong Y, Leppert MF, Lin J, Hunt SC, Rich SS, Arnett DK, Myers RH, Eckfeldt J, Williams RR, Province MA. No evidence of linkage between the very-low-density lipoprotein receptor gene and fasting serum insulin or homeostasis model assessment insulin resistance index: the NHLBI Family Heart Study. Metabolism. 2000 Mar;49(3):293-7.

Slattery ML, Potter JD, Ma K-N, Caan BJ, Leppert M, Samowitz W. Western diet, family history of colorectal cancer, NAT2, GSTM-1 and risk of colon cancer. Cancer Causes Control. 2000 Jan;11(1):1-8.

Flanigan KM, Kerr L, Bromberg MB, Leonard C, Tsuruda J, Zhang P, Gonzalez-Gomez I, Cohn R, Campbell KP, Leppert MF. Congenital muscular dystrophy with rigid spine syndrome: a clinical, pathological, radiological, and genetic study. Ann Neurol. 2000 Feb;47(2):152-61.

Leppert MF and Singh N. Susceptibility genes in human epilepsy. Semin Neurol. 1999 19(4):397-405.

Bovill EG, Hasstedt SJ, Leppert MF, Long GL. Hereditary thrombophilia as a model for multigenic disease. Thromb Haemost. 1999 Aug;82(2):662-6.

Spirio L, Green J, Robertson J, Robertson M, Otterud B, Sheldon J, Howse E, Green R, Groden J, White R, Leppert M. The identical 5′ splice-site acceptor mutation in five attenuated APC families from Newfoundland demonstrates a founder effect. Hum Genet. 1999 Nov;105(5):388-98.

Katsanis N, Lewis RA, Stockton DW, Mai PMT, Baird L, Beales PL, Leppert M, Lupski JR. Delineation of the critical interval of Bardet-Biedl Syndrome 1 (BBS1) to a small region of 11q13, through linkage and haplotype analysis of 91 pedigrees. Am J Hum Genet. 1999 Dec;65(6):1672-1679.

Singh N, Charlier C, Peiffer A, Stauffer D, Melis R, Enoch MA, Goldman D, Rogers S, Anderson VE, Leppert M. Genes for rare idiopathic generalized epilepsies: BFNC. Adv Neurol. 1999 79:341-50.

Peiffer A, Thompson J, Charlier C, Otterud B, Varvil T, Pappas C, Barnitz C, Gruenthal K, Kuhn R, Leppert M. A locus for febrile seizures (FEB3) maps to chromosome 2q23-24. Ann Neurol. 1999 46:671-78.

Coon H, Leppert MF, Kronenberg F, Province MA, Myers RH, Arnett DK, Eckfeldt JH, Heiss G, Williams RR, Hunt SC. Evidence for a major gene accounting for mild elevation in LDL cholesterol: the NHLBI Family Heart Study. Ann Hum Genet. 1999 Sep;63(Pt 5):401-12.

Shroyer NF, Lewis RA, Allikmets R, Singh N, Dean M, Leppert M, Lupski JR. The rod photoreceptor ATP-binding cassette transporter gene, ABCR, and retinal disease: from monogenic to multifactorial. Vision Res. 1999 39(14):2537-44.

Slattery ML, Potter JD, Samowitz W, Schaffer D, Leppert M. Methylenetetrahydrofolate reductase, diet, and risk of colon cancer. Cancer Epidemiol Biomarkers Prev. 1999 Jun;8(6):513-18.

MacDougall M, Jeffords LG, Gu TT, Knight CB, Frei G, Reus BE, Otterud B, Leppert M, Leach RJ. Genetic linkage of the dentinogenesis imperfecta type III locus to chromosome 4q. J Dent Res. 1999 Jun;78(6):1277-82.

Samowitz WS, Slattery ML, Potter JD, Leppert MF. BAT-26 and BAT-40 instability in colorectal adenomas and carcinomas and germline polymorphisms. Am J Pathol. 1999 Jun;154(6):1637-41.

Elbein SC, Hoffman MD, Teng K, Leppert MF, Hasstedt SJ. A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians. Diabetes. 1999 May;48(5):1175-82.

Peiffer A, Singh N, Leppert M, Dobyns WB, Carey JC. Microcephaly with simplified gyral pattern in six related children. Am J Med Genet. 1999 84:137-144.

Numasawa T, Koga H, Ueyama K, Maeda S, Sakou T, Harata S, Leppert M, Inoue I. Human retinoic X receptor beta: complete genomic sequence and mutation search for ossification of posterior longitudinal ligament of the spine. J Bone Miner Res. 1999 Apr;14(4):500-8.

Leppert M and Singh N. Benign familial neonatal epilepsy with mutations in two potassium channel genes. Curr Opin Neurol. 1999 Apr 12(2):143-7.

Hunt SC, Province MA, Atwood LD, Sholinsky P, Lalouel J-M, Rao DC, Williams RR, Leppert MF. No linkage of the lipoprotein lipase locus to hypertension in Caucasians. J Hypertens. 1999 17(1):39-43.

Hedera P, Rainier S, Alvarado D, Zhao X, Williamson J, Otterud B, Leppert M, Fink JK. Novel locus for autosomal dominant hereditary spastic paraplegia, on chromosome 8q. Am J Hum Genet. 1999 Feb;64(2):563-9.

Hobbs MR, Pole AR, Pidwirny GN, Rosen IB, Zarbo RJ, Coon H, Heath H III, Leppert M, Jackson CE. Hyperparathyroidism-jaw tumor syndrome: the HRPT2 locus is within a 0.7-cM region on chromosome 1q. Am J Hum Genet. 1999 Feb;64(2):518-25.

Lewis RA, Shroyer NF, Singh N, Allikmets R, Hutchinson A, Li Y, Lupski JR, Leppert M, Dean M. Genotype/phenotype analysis of a photoreceptor-specific ATP-binding cassette transporter gene, ABCR, in Stargardt disease. Am J Hum Genet. 1999 64(2):422-34.

Kampman E, Slattery ML, Bigler J, Leppert M, Samowitz W, Caan BJ, Potter JD. Meat consumption, genetic susceptibility, and colon cancer risk: A United States multicenter case-control study. Cancer Epidemiol Biomarkers Prev. 1999 Jan;8:15-24.

Naumova AK, Olien L, Bird LM, Smith M, Verner AE, Leppert M, Morgan K, Sapienza C. Genetic mapping of X-linked loci involved in skewing of X chromosome inactivation in the human. Eur J Hum Genet. 1998 Nov-Dec;6(6):552-62.

Slattery ML, Potter JD, Samowitz W, Bigler J, Caan B, and Leppert MF. NAT2, GSTM-1, cigarette smoking, and risk of colon cancer. Cancer Epidemiol Biomarkers Prev. 1998 7:1079-84.

Elliott CG, Leppert MF, Alexander GJ, Ward K, Nelson L, and Pietra GG. Factor V Leiden is not common in patients diagnosed with primary pulmonary hypertension. Eur Respir J. 1998 12:1177-80.

Goodman BK, Shaffer LG, Rutberg J, Leppert MF, Harum K, Gagos S, Ray JH, Bialer MG, Zhou X, Pletcher BA, Shapira SK, Geraghty MT. Inherited duplication Xq27-qter at Xp22.3 in severely affected males: molecular cytogenetic evaluation and clinical description in three unrelated families. Am J Med Genet. 1998 Dec 4;80(4):377-384.

Spirio LN, Samowitz W, Robertson J, Robertson M, Burt RW, Leppert MF, and White R. Alleles of APC modulate the frequency and classes of mutations that lead to colon polyps. Nat Genet. 1998 20:385-388.

Rainier S, Jones SM, Esposito C, Guice E, Otterud B, Leppert M, and Fink JK. Analysis of microtubule-associated protein 1a gene in hereditary spastic paraplegia. Neurology. 1998 51:1509-10.

Spirio LN, Dixon DA, Robertson J, Robertson M, Barrows J, Traer E, Burt RW, Leppert MF, White R, and Prescott SM. The inducible prostaglandin biosynthetic enzyme, cyclooxygenase 2, is not mutated in patients with attenuated adenomatous polyposis coli. Cancer Res. 1998 58:4909-4912.

Gubarev MI, Jenkin JC, Otterud BE, Leppert MF, Schallheim JM, and Beatty PG. Localization to chromosome 11 of a gene encoding a human minor histocompatibility antigen. Exp Hematol. 1998 26:976-81.

Koga H, Sakou T, Taketomi E, Hayashi K, Numasawa T, Harata S, Yone K, Matsunaga S, Otterud BE, Inoue I, and Leppert MF. Genetic mapping of ossification of the posterior longitudinal ligament of the spine. Am J Hum Genet. 1998 62:1460-1467.

Naumova AK, Leppert M, Barker DF, Morgan K, and Sapienza C. Parental origin-dependent, male offspring-specific transmission-ratio distortion at loci on the human X chromosome. Am J Hum Genet. 1998 62:1493-9.

Bejjani BA, Lewis RA, Tomey KF, Anderson KL, Dueker DK, Jabak M, Astle WF, Otterud B, Leppert M, and Lupski JR. Mutations in CYP1B1, the gene for cytochrome P4501B1, are the predominant cause of primary congenital glaucoma in Saudi Arabia. Am J Hum Genet. 1998 62:325-33.

Charlier C, Singh NA, Ryan SG, Lewis T, Reus B, Leach RJ, and Leppert MF. A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family. Nat Genet. 1998 18:53-55.

Singh N, Charlier C, Stauffer D, DuPont BR, Leach RJ, Melis R, Ronen GM, Bjerre I, Quattlebaum T, Murphy JV, McHarg ML, Gagnon D, Rosales TO, Peiffer A, Anderson VE and Leppert MF. A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns. Nat Genet. 1998 18:25-29.

Elbein SC, Leppert MF, Hasstedt S. Uncoupling protein 2 region on chromosome 11q13 is not linked to markers of obesity in familial type 2 diabetes. Diabetes. 1997 46(12):2105-7.

Cody JD, Singer FR, Roodman GD, Otterud BE, Lewis TB, Leppert MF, and Leach RJ. Genetic linkage of Paget disease of the bone to chromosome 18q. Am J Hum Genet. 1997 Nov;61(5):1117-22.

Hasstedt SJ, Hoffman M, Leppert MF and Elbein S. Recessive inheritance of obesity in familial non-insulin-dependent diabetes mellitus, and lack of linkage to nine candidate genes. Am J Hum Genet. 1997 1:668-677.

Horwitz M, Benson KF, Li FQ, Wolff J, Leppert MF, Hobson L, Mangelsdorf M, Yu S, Hewett D, Richards RI, and Raskind WH. Genetic heterogeneity in familial acute myelogenous leukemia: evidence for a second locus at chromosome. 16q21-23.2. Am J Hum Genet. 1997 Oct;61(4):873-81.

Allikmets R, Shroyer NF, Singh N, Seddon J-M, Lewis RA, Bernstein P, Peiffer A, Zabriskie N, Li Y, Hutchinson A, Dean M, Lupski JR and Leppert MF. Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science. 1997 277:1805-1807.

Zwick A, Munir M, Ryan CK, Gian J, Burt RW, Leppert MF, Spirio L, and Chey WY. Gastric adenocarcinoma and dysplasia in fundic gland polyps of a patient with attenuated adenomatous polyposis coli. Gastroenterology. 1997 113:659-663.

Allikmets R, Singh N, Sun, H, Shroyer NF, Hutchinson A, Chidambaram A, Gerrard B, Baird L, Stauffer D, Peiffer A, Rattner A, Smallwood P, Li Y, Anderson KL, Lewis RA, Nathans J, Leppert M, Dean M, and Lupski, J R. A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy Nat Genet. 1997 Mar;15(3):236-246.

Elbein SC, Hoffman MD, Mayorga RA, Barrett KL, Leppert MF, and Hasstedt S. Do non-insulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus share genetic susceptibility loci? An analysis of putative IDDM susceptibility regions in familial NIDDM. Metabolism. 1997 46:48-52.

Gubarev MI, Jenkin JC, Leppert MF, Buchanan GS, Otterud BE, Guilbert DA, and Beatty PG. Localization to chromosome 22 of a gene encoding a human minor histocompatibility antigen. J Immunol. 1996 15;157(12):5448-54.

Elbein SC, Hoffman M, Barrett K, Wegner K, Miles C, Bachman K, Berkowitz D, Shuldiner AR, Leppert MF, and Hasstedt S. Role of the beta 3-adrenergic receptor locus in obesity and noninsulin-dependent diabetes among members of Caucasian families with a diabetic sibling pair. J Clin Endocrinol Metab. 1996 81(12):4422-7.

Anderson LK, Lewis RA, Bejjani BA, Baird L, Otterud BE, Tomey KF, Astle WF, Dueker DK, Leppert MF, and Lupski JR. A gene for primary congenital glaucoma is not linked to the locus on chromosome 1q for autosomal dominant juvenile-onset open angle glaucoma. J Glaucoma. 1996 5:416-421.

Flanigan KM, Gardner K, Alderson K, Galster B, Otterud BE, Leppert MF, Kaplan C, and Ptacek LJ. Autosomal dominant spinocerebellar ataxia with sensory asonal neuropathy (SCA4): clinical description and genetic localization to chromosome 16q22.1. Am J Hum Genet. 1996 59:392-399.

Fink JK, Rainer S, Wilkowski J, Jones SM, Kume A, Hedera P, Albin R, Mathay J, Girbach L, Varvil T, Otterud BE, Leppert MF. Paroxysmal dystonic choreoathetosis: tight linkage to chromosome 2q. Am J Hum Genet. 1996 59:140-145.

Ho CY, Otterud B, Legare RD, Varvil T, Saxena R, DeHart DB, Kohler SE, Aster JC, Dowton SB, Li FP, Leppert M, and Gilliland DG. Linkage of a familial platelet disorder with a propensity to develop myeloid malignancies to human chromosome 21q22.1-22.2. Blood. 1996 87:5218-5224.

Naumova AK, Plenge RM, Bird LM, Leppert M, Morgan K, Willard HF, and Sapienza C. Heritability of X chromosome-inactivation phenotype in a large family. Am J Hum Genet. 1996 58:1111-1119.

McMahon WM, van de Wetering BJ, Filloux F, Betit K, Coon H, and Leppert MF. Bilineal transmission and phenotypic variation of Tourette’s disorder in a large pedigree. J Am Acad Child Adolesc Psychiatry. 1996 35(5):672-80.

Heath III H, Odelberg S, Jackson CE, Teh BT, Hayward N, Larsson C, Buist NRM, Krapcho KJ, Hung BC, Capuano IV, Garrett JE, and Leppert MF. Clustered inactivating mutations and benign polymorphisms of the calcium receptor gene in a familial benign hypocalciuric hypercalcemia suggest receptor functional domains. J Clin Endocrinol Metab. 1996 Apr;81(4):1312-1317.

Spirio LN, Kutchera W, Winstead MV, Pearson B, Kaplan C, Robertson M, Lawrence E, Burt RW, Tischfield JA, Leppert MF, Prescott SM, and White R. Three secretory phospholipase A(2) genes that map to human chromosome 1P35-36 are not mutated in individuals with attenuated adenomatous polyposis coli. Cancer Res. 1996 1;56(5):955-8.

Fink JK, Jones SM, Sharp GB, Lange BM, Otterud BE, and Leppert MF. Hereditary spastic paraplegia linked to chromosome 15q: Analysis of candidate genes. Neurology. 1996 46(3):835-6.

Elbein SC, Bragg KL, Hoffman MD, Mayorga RA, and Leppert MF. Linkage studies of NIDDM with 23 chromosome 11 markers in a sample of whites of northern European descent. Diabetes. 1996 45(3):370-5.

Anderson KL, Baird L, Lewis RA, Chinault AC, Otterud BE, Leppert MF, and Lupski JR. A YAC contig encompassing the recessive Stargardt disease gene (STGD) on chromosome 1p. Am J Hum Genet. 1995 57:1351 – 53.

Elbein SC, Chiu KC, Hoffman MD, Mayorga RA, Bragg KL, and Leppert MF. Linkage analysis of 19 candidate regions for insulin resistance in familial NIDDM. Diabetes. 1995 44:1259-65.

Elliott G, Alexander G, Leppert MF, Yeates S, and Kerber R. Coancestry in apparently sporadic primary pulmonary hypertension. Chest. 1995 108: 973-77.

Hasstedt SJ, Leppert MF, Filloux F, van de Wetering BJ, and McMahon WM. Intermediate inheritance of Tourette syndrome, assuming assortative mating. Am J Hum Genet. 1995 57:682-9.

Gouw LG, Kaplan CD, Haines JH, Digre KB, Rutledge SL, Matilla A, Leppert MF, Zoghbi HY, and Ptacek LJ. Retinal degeneration characterizes spinocerebellar ataxia mapping to chromosome 3p. Nat Genet. 1995 10:89-93.

Klanke CA, Su YR, Callen DF, Wang Z, Meneton P, Baird N, Kandasamy RA, Orlowski J, Otterud BE, Leppert MF, et al. Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1. Genomics. 1995 25:615-22.

Fink JK, Sharp GB, Lange BM, Wu CB, Haley T, Otterud B, Peacock M, Leppert MF. Autosomal dominant, familial spastic paraplegia, type I: clinical and genetic analysis of a large North American family. Neurology. 1995 45(2):325-31.

Bleyl S, Nelson L, Odelberg SJ, Ruttenberg HD, Otterud BE, Leppert MF, and Ward K. A gene for familial total anomalous pulmonary venous return maps to chromosome 4p13-q12. Am J Hum Genet. 1995 56: 408-15.

Naumova AK, Olien L, Bird LM, Slamka C, Fonseca M, Verner AE, Wang M, Leppert MF, Morgan K, and Sapienza C. Transmission-ratio distortions of X chromosomes among male offspring of females with skewed X-inactivation. Dev Genet. 1995 17:198-205.

Fink JK, Wu CT, Jones SM, Sharp GB, Lange BM, Lesicki A, Reinglass T, Varvil TS, Otterud BE, Leppert M. Autosomal dominant familial spastic paraplegia: tight linkage to chromosome 15q. Am J Hum Genet. 1995 56:188-92.

Melis R, Stauffer D, Zhao X, Zhu XL, Albrecht B, Pongs O, Brothman A, and Leppert MF. Physical and genetic localization of a Shab subfamily potassium channel (KCNB1) gene to chromosomal region 20q13.2. Genomics. 1995 25:285-7.

Klanke CA, Su YR, Varvil TS, Otterud BE, Leppert M, and Menon AG. Dinucleotide repeat polymorphism from a cosmid containing the human anion exchanger isoform 3 (SLC2C) gene. Hum Mol Genet. 1994 3(11): 2086.

Borish L, Mascali JJ, Klinnert M, Leppert MF, and Rosenwasser LJ. SSC polymorphisms in interleukin genes. Hum Mol Genet. 1994 Sep;3(9):1710.

Su YR, Klanke CA, Houseal TW, Linn SC, Burk SE, Varvil TS, Otterud BE, Shull GE, Leppert MF, and Menon AG. Molecular cloning and physical and genetic mapping of the human anion exchanger isoform 3 (SLC2C) gene to chromosome 2q36. Genomics. 1994 Aug;22(3):605-9.

Elbein SC, Hoffman M, Ridinger D, Otterud BE, and Leppert MF. Description of a second microsatellite marker and linkage analysis of the muscle glycogen synthase locus in familial NIDDM. Diabetes. 1994 43: 1061-5.

German J, Roe AM, Leppert MF, and Ellis NA. Bloom syndrome: An analysis of consanguineous families assigns the locus mutated to chromosome band 15q26.1. Proc Natl Acad Sci USA. 1994 91:6669-6673.

Jorde LB, Watkins WS, Carlson M, Groden J, Albertsen H, Thliveris A, and Leppert MF. Linkage disequilibrium predicts physical distance in the adenomatous polyposis coli region. Am J Hum Genet. 1994 54:884-898

Leppert MF, Baird L, Anderson KL, Otterud B, Lupski JR, and Lewis RA. Bardet-Biedl syndrome is linked to DNA markers on chromosome 11q and is genetically heterogeneous. Nat Genet. 1994 7:108-112

Coon H, Jensen S, Holik J, Hoff M, Myles-Worsley M, Reimherr F, Wender P, Waldo M, Freedman R, Leppert MF, and Byerley W. Genomic Scan for Genes Predisposing to Schizophrenia. Am J of Med Genet (Neuropsych Genet). 1994 54:59-71.

Lynch HT, Fusaro RM, Sandberg AA, Bixenman HA, Johnsen LR, Lynch JF, Ramesh KH, and Leppert MF. Chromosome instability and the FAMM syndrome. Cancer Genet Cytogenet. 1993 71:27-39.

Leppert MF, McMahon W, Quattlebaum T, Bjerre I, Zonana J, Shevell M, Andermann E, Rosales T, Ronen G, Connolly M, and Anderson VE. Searching for human epilepsy genes: a progress report. Brain Pathol. 1993 3:357-369

Ewart AK, Morris CA, Atkinson D, Jin W, Sternes K, Spallone P, Stock AD, Leppert MF, Keating MT. Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome. Nat Genet. 1993 Sep;5(1):11-16.

Enjyoji K, Emi M, Mukai T, Imada M, Leppert MF, Lalouel J-M, Kato H. Human tissue factor pathway inhibitor (TFPI) gene: complete genomic structure and localization on the genetic map of chromosome 2q. Genomics. 1993 Aug;17(2):423-428.

Curran M, Atkinson D, Timothy K, Vincent GM, Moss AJ, Leppert MF, and Keating M. Locus heterogeneity of autosomal dominant long QT syndrome. J Clin Invest. 1993 92:799-803.

Williams RR, Hunt SC, Schumacher MC, Hegele RA, Leppert MF, Ludwig EH, Hopkins PN. Diagnosing heterozygous familial hypercholesterolemia using new practical criteria validated by molecular genetics. Am J Cardiol. 1993 Jul 15;72(2):171-176.

Ronen GM, Rosales TO, Connolly M, Anderson VE, and Leppert MF. Seizure characteristics in chromosome 20 benign familial neonatal convulsions. Neurology. 1993 43:1355-1360

Heath III H, Jackson CE, Otterud BE, and Leppert MF. Genetic linkage analysis in familial benign (hypocalciuric) hypercalcemia: evidence for locus heterogeneity. Am J Hum Genet. 1993 53:193-200.

Coon H, Jensen S, Hoff M, Holik J, Plaetke R, Reimherr F, Wender P, Leppert MF, and Byerley W. A genome-wide search for genes predisposing to manic-depression, assuming autosomal dominant inheritance. Am J Hum Genet. 1993 52:1234-1249.

Rose J, Gerken S, Lynch S, Pisani P, Varvil T, Otterud B, and Leppert MF. Genetic susceptibility in familial multiple sclerosis not linked to the myelin basic protein gene. Lancet. 1993 341:1179-1181.

Bowcock AM, Gerken SC, Barnes RI, Shiang R, Jabs EW, Warren AC, Antonarakis S, Retief AE, Vergnaud G, Leppert MF, et al. The CEPH consortium linkage map of human chromosome 13. Genomics. 1993 May;16(2):515-519.

Gerken S, Leppert MF, O’Connell P, Cavenee W, James CD, Ballard L, Stauffer D, Elsner T, Plaetke R, Lalouel J-M, and White R. A genetic linkage map with 29 loci spanning human chromosome 13q. Genomics. 1993 16:515-519.

Ewart A, Morris C, Ensing GJ, Loker J, Moore C, Leppert MF, and Keating M. A human vascular disorder, supravalvular aortic stenosis, maps to chromosome 7. Proc Natl Acad Sci USA. 1993 90:3226-3230.

Curran M, Atkinson D, Ewart A, Morris C, Leppert M, and Keating M. The elastin gene is disrupted by a translocation associated with supravalvular aortic stenosis. Cell. 1993 73:159-168.

Ptacek L, Gouw L, Kwiecinski H, McManis P, Mendell J, Barohn R, George Jr. A, Barchi R, Robertson M, and Leppert MF. Sodium channel mutations in paramyotonia congenita and hyperkalemic periodic paralysis. Ann Neurol. 1993 33:300-307.

Spirio L, Nelson L, Ward K, Burt R, White R, and Leppert MF. A CA-repeat polymorphism close to the adenomatous polyposis coli (APC) gene offers improved diagnostic testing for familial APC. Am J Hum Genet. 1993 52:286-296.

Jensen S, Plaetke R, Holik J, Hoff M, Myles-Worsley M, Leppert MF, Coon H, Vest K, Freedman R, Waldo M, Zhou Q, Litt M, Civelli O, and Byerley W. Linkage analysis of schizophrenia: The D1 dopamine receptor gene and several flanking DNA markers. Hum Hered. 1993 43:58-62.

O’Connell P, Plaetke R, Matsunami N, Odelberg SJ, Jorde L, Chance P, Leppert MF, Lalouel J-M, and White R. An extended genetic linkage map and an “index” map for human chromosome 17. Genomics. 1993 15:38-47.

Hoehe MR, Ehrenreich H, Otterud BE, Caenazzo L, Plaetke R, Zander H, and Leppert MF. The human endothelin-1 gene (EDN1) encoding a peptide with potent vasoactive properties maps distal to HLA on chromosome arm 6p in close linkage to D6S89. Cytogenet Cell Genet. 1993 62:131-135

Keats B, Todorov A, Atwood L, Pelias M, Hejtmancik J, Kimberling W, Leppert MF, Lewis R, and Smith R. Linkage studies of Usher syndrome type 1: exclusion results from the Usher Syndrome Consortium. Genomics. 1992 14:707-714.

Huff V, Reeve A, Leppert M, Strong L, Douglass E, Geiser C, Li F, Meadows A, Callen D, Lenoir G, and Saunders G. Nonlinkage of 16q markers to familial predisposition to Wilms’ Tumor. Cancer Res. 1992 52:6117-6120.

Vincent GM, Timothy KW, Leppert MF, and Keating M. The spectrum of symptoms and QT intervals in carriers of the gene for the long-QT syndrome. N Engl J Med. 1992 327:846-852.

Heath III H, Leppert MF, Lifton R, and Penniston J. Genetic linkage analysis in familial benign hypercalcemia using a candidate gene strategy. I. Studies in four families. J Clin Endocrinol Metab. 1992 75:846-851.

Lynch H, Watson P, Smyrck T, Lanspa S, Boman B, Boland C, Lynch J, Cavalieri R, Leppert MF, White R, Sidransky D, and Vogelstein B. Colon cancer genetics. Cancer. 1992 70:1300-1312.

Hoehe M, Plaetke R, Otterud B, Stauffer D, Holik J, Byerley W, Baetge E, Gershon E, Lalouel J-M, and Leppert MF. Genetic linkage of the human gene for phenylethanolamine N-methyltransferase (PNMT), the adrenaline-synthesizing enzyme, to DNA markers on chromosome 17q21-q22. Hum Mol Genet. 1992 3:175-178.

Ptacek L, George A, Barchi R, Griggs R, Riggs J, Robertson M, and Leppert MF. Mutations in an S4 segment of the adult skeletal muscle sodium channel gene cause paramyotonia congenital. Neuron. 1992 8:891-897.

Ptacek L, Ziter F, Roberts J, and Leppert MF. Evidence of genetic heterogeneity among the non-dystrophic myotonias. Neurology. 1992 42:1046-1048.

Lynch S, Rose J, Petajan J, and Leppert MF. Discordance of the T-cell receptor alpha-chain gene in familial multiple sclerosis. Neurology. 1992 42:839-844.

Spirio L, Nelson L, Joslyn G, Leppert MF, White R. A CA repeat 30-70 Kb downstream from the adenomatous polyposis coli (APC) gene. Nucleic Acids Res. 1992 Feb 11;20(3):642.

Epstein N, Fananapazir L, Lin H, Mulvihill J, White R, Lalouel J-M, Lifton R, Nienhuis A, and Leppert MF. Evidence of genetic heterogeneity in five kindreds with familial hypertrophic cardiomyopathy. Circulation. 1992 82:635-47.

Ptacek L, Tawil R, Griggs R, Storvick D, and Leppert MF. Linkage of atypical myotonia congenita to a sodium channel locus. Neurology. 1992 42:431-433.

McMahon W, Leppert MF, Filloux F, van-de-Wetering BJ, and Hasstedt S. Tourette symptoms in 161 related family members. Adv Neurol. 1992 58:159-165.

Byerley W, Plaetke R, Hoff M, Jensen S, Holik J, Reimherr F, Mellon C, Wender P., O’Connell P, and Leppert MF. Tyrosine hydroxylase gene not linked to manic-depression in seven of eight pedigrees. Hum Hered. 1992 42:259-263.

Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Alabertsen H, Joslyn G, Stevens J, Spirio L, Robertson M, Sargeant L, Krapcho K, Wolff E, Burt R, Hughes JP, Warrington J, McPherson J, Wasmuth J, LePaslier D, Abderrahim H, Cohen D, Leppert M, White R. Identification and characterization of the familial adenomatous polyposis coli gene. Cell. 1991 66:589-600.

Ptacek L, George Jr. A, Griggs R, Tawil R, Kallen R, Barchi R, Robertson M, and Leppert MF. Identification of a mutation in the gene causing hyperkalemic periodic paralysis. Cell. 1991 67:1021-1027.

Keating M, Dunn C, Atkinson D, Timothy K, Vincent GM, and Leppert MF. Consistent linkage of the long QT syndrome to the Harvey Ras-1 locus on chromosome 11. Am J Hum Genet. 1991 49:1335-1339.

Spirio L, Nelson L, Joslyn G, Leppert MF and White R. A CA repeat 30-70 KB downstream from the adenomatous polyposis coli (APC) gene. Nucleic Acids Res. 1991 19: 6348.

White MB, Leppert MF, Nielsen D, Zielenski J, Gerrard B, Stewart C, Dean M. A de novo cystic fibrosis mutation: CGA (Arg) to TGA (stop) at codon 851 of the CFTR gene. Genomics. 1991 Nov;11(3):778-779.

Ptacek L, Trimmer J, Agnew WS, Roberts JW, Petajan JH, and Leppert MF. Paramyotonia congenita and hyperkalemic periodic paralysis map to the same sodium channel gene locus. Am J Hum Genet. 1991 49:851-854.

Lynch S, Rose J, Petajan J, Stauffer D, Kamerath C, and Leppert MF. Discordance of T-Cell receptor beta-chain genes in familial multiple sclerosis. Ann Neurol. 1991 30:402-410.

Ptacek L, Tyler F, Trimmer J, Agnew W, and Leppert MF. Analysis in a large hyperkalemic periodic paralysis pedigree supports tight linkage to a sodium channel locus. Am J Hum Genet. 1991 49:378-382.

Keating M, Atkinson D, Dunn C, Timothy K, Vincent GM, and Leppert MF. Linkage of a cardiac arrhythmia, the long QT syndrome, and the Harvey ras-1 Gene. Science. 1991 252:704-706.

Dean M, Stewart C, Perry A, Stauffer D, Otterud BE, White R, Leppert MF. D7S448 detects a HindIII polymorphism located in the centromere region of chromosome 7. Nucleic Acids Res. 1991 Jan 11;19(1):200.

Leppert MF and Lewis R.A. Human genetic mapping and inherited deafness syndromes. Ann N Y Acad Sci. 1991 630:38-48.

Takahashi E, Hori T, O’Connell P, Leppert MF, and White R. Mapping of the MYC gene to band 8q24.12 — q24.13 by R-banding and distal to fra(8)(q24.11), FRA8E, by fluorescence in situ hybridization. Cytogenet Cell Genet. 1991 57:109-111.

Leppert MF, Anderson VE, White R. The discovery of epilepsy genes by genetic linkage. Epilepsy Res Suppl. 1991 4:181-188.

Dean M, Gerrard B, Stewart C, Krueger L, Holsclaw D, Quittell L, Baranov V, Kapronov N, Leppert MF, Amos J, et al. Identification of cystic fibrosis mutations. Adv Exp Med Biol. 1991 290:45-51.

Dean M, Stewart C, Perry A, Stauffer D, Otterud BE, White R, Leppert MF. D7S449 detects a HindIII polymorphism tightly linked to the MET gene on chromosome 7. Nucleic Acids Res. 1990 Dec 11;18(23):7199.

Chance P, Bird T, O’Connell P, Lipe H, Lalouel J-M, and Leppert MF. Genetic linkage and heterogeneity in type 1 Charcot-Marie-Tooth disease (hereditary motor and sensory neuropathy type I). Am J Hum Genet. 1990 47:915-925.

Takahashi E, Hori T, O’Connell P, Leppert MF, and White R. R-banding and nonisotopic in situ hybridization: precise localization of the human type II collagen gene (COL2A1). Hum Genet. 1990 86:14-16.

Julier C, Nakamura Y, Lathrop M, O’Connell P, Leppert MF, Litt M, Mohandas T, Lalouel J-M, and White R. A detailed genetic map of the long arm of chromosome 11. Genomics. 1990 7:335-345.

Dean M, White MB, Amos J, Gerrard B, Stewart C, Khaw KT, and Leppert MF. Multiple mutations in highly conserved residues are found in mildly affected cystic fibrosis patients. Cell. 1990 61:863-870.

Lewis RA, Otterud B, Stauffer D, Lalouel J-M, and Leppert MF. Mapping recessive ophthalmic diseases: linkage of the locus for Usher syndrome type II to a DNA marker on Chromosome 1q. Genomics. 1990 7:250-256.

Ward R, O’Connell P, Carey J, Leppert MF, Jolley S, Plaetke R, Ogden B, and White R. Diagnosis of neurofibromatosis 1 by using tightly linked, flanking DNA markers. Am J Hum Genet. 1990 May;46(5):943-949.

Brzustowicz L, Lehner T, Castilla L, Penchaszadeh G, Wilhelmsen K, Daniels R, Davies K, Leppert MF, Ziter F, Wood D, Dubowitz V, Zerres K, Hausmanowa-Petruscwicz I, Ott J, Munsat TL, and Gilliam TC. Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q11.2-13.3. Nature. 1990 44:540-541.

Leppert MF, Burt R, Hughes JP, Samowitz W, Nakamura Y, Woodward S, Gardner E, Lalouel J-M, and White R. Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps. New Eng J Med. 1990 322:904-908.

Julier C, Nakamura Y, Lathrop M, O’Connell P, Leppert MF, Mohandas T, Lalouel J-M, and White R. A primary map of 24 loci on human chromosome 16. Genomics. 1990 6:419-427.

Spurr NK and Leppert MF. Report of the committee on the genetic constitution of chromosome 2. Cytogenet Cell Genet. 1990 55:86-91.

Leppert MF. Gene mapping and other tools for discovery. Epilepsia. 1990 31(3):S11-18.

Takahashi E, Hori T, Lawrence J, McNeil J, Singer R, O’Connell P, Leppert MF, and White R. Human type II collagen gene (COL2A1) assigned to chromosome 12q13.1-q13.2 by in situ hybridization with biotinylated DNA probe. Jpn J Hum Genet. 1989 34:307-311.

Nakamura Y, Leppert MF, O’Connell P, Lathrop M, Lalouel J-M, and White R. A genetic linkage map for markers for human chromosome 20. Genomics. 1989 5:945-947.

Lathrop M, O’Connell P, Leppert MF, Nakamura Y, Farrall M, Tsui L-C, Lalouel J-M, and White R. Twenty-five loci form a continuous linkage map of markers for human chromosome 7. Genomics. 1989 5:866-873.

O’Connell P, Lathrop M, Nakamura Y, Leppert MF, Lalouel J-M, and White R. Twenty loci form a continuous linkage map of markers for human chromosome 2. Genomics. 1989 5:738-745.

Odelberg S, Plaetke R, Eldgridge R, Ballard L, O’Connell P, Nakamura Y, Leppert MF, Lalouel J-M, and White R. Characterization of VNTR loci by high-resolution agarose gel electrophoresis: Implications for parentage testing and forensic individualization. Genomics. 1989 5:915-924.

Kern S, Fearson E, Tersmette K, Enterline J, Leppert MF, Nakamura Y, White R, Vogelstein B, and Hamilton S. Clinical and pathological associations with allelic loss in colorectal carcinoma. JAMA. 1989 262:1952.

Litt M, Litt R, Ballard L, and Leppert MF. An anonymous single-copy clone, p30-1-60, identifies a frequent RFLP on chromosome 3p [HGM9 no. D3S86]. Nucleic Acids Res. 1989 Apr 11;17(7):2883.

Leppert MF, Anderson VE, Quattlebaum T, Stauffer D, O’Connell P, Nakamura Y, Lalouel J-M, White R. Benign familial neonatal convulsions linked to genetic markers on chromosome 20. Nature 1989 Feb 16;337(6208):647-648.

Byerley W, O’Connell P, Lalouel J-M, Mellon J, Wasmuth J, Nakamura Y, Leppert M, and White R. Mapping genes for manic depression and schizophrenia with DNA markers. Trends Neurosci. 1989 Feb;12(2):46-48.

O’Connell P, Lathrop M, Nakamura Y, Leppert MF, Ardinger RH, Murray JL, Lalouel J-M, and White R. Twenty-eight loci form a continuous linkage map of markers for human chromosome 1. Genomics. 1989 4:12-20.

Nakamura Y, Lathrop M, O’Connell P, Leppert M, Lalouel J-M, and White R. Frequent recombination is observed in the distal end of the long arm of chromosome 14. Genomics. 1989 4:76-81.

White R, Leppert MF, Nakamura Y, O’Connell P, Lathrop M, and Lalouel J-M. Linkage maps of human chromosomes. Genome. 1989 31(2):1066-1072.

Ledbetter DH, Rich DC, O’Connell P, Leppert M, and Corey JC. Precise localization of NF1 to 17q11.2 by balanced translocation. Am J Hum Genet. 1989 44:20-24.

O’Connell P, Lathrop M, Leppert MF, Nakamura Y, Muller U, Lalouel J-M, and White R. Twelve loci form a continuous linkage map for human chromosome 18. Genomics. 1988 Nov;3(4):367-372.

Lathrop M, Nakamura Y, O’Connell P, Leppert MF, Woodward S, Lalouel J-M, and White R. A mapped set of genetic markers for human chromosome 9. Genomics. 1988 Nov;3(4):361-366.

Nakamura Y, Lathrop GM, O’Connell P, Leppert MF, Lalouel J-M, White R. A mapped set of DNA markers for human chromosome 15. Genomics. 1988 Nov;3(4):342-346.

Nakamura Y, Lathrop M, Bragg T, Leppert MF, O’Connell P, Jones C, Lalouel J-M, and White R. An extended genetic linkage map of markers for human chromosome 10. Genomics. 1988 Nov;3(4):389-392.

Nakamura Y, Lathrop M, Leppert M, Dobbs M, Wasmuth J, Wolff E, Carlson M, Fujimoto E, Krapcho K, Sears T, et al. Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5. Am J Hum Genet. 1988 Nov;43(5):638-644.

Leppert MF, Breslow JL, Wu L, Hasstedt S, O’Connell P, Lathrop M, Williams RR, White R, Lalouel J-M. Inference of a molecular defect of apolipoprotein B in hypobetalipoproteinemia by linkage analysis in a large kindred. J Clin Invest. 1988 Oct 11;16(19):9354.

Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert MF, Nakamura Y, White R, Smits AM, Bos JL. Genetic alterations during colorectal-tumor development. N Engl J Med. 1988 Sep 1;319(9):525-532.

Nakamura Y, Lathrop M, O’Connell P, Leppert MF, Lalouel J-M, White R. A primary map of ten DNA markers and two serological markers for human chromosome 19. Genomics. 1988 Jul;3(1):67-71.

Nakamura Y, Lathrop GM, O’Connell P, Leppert MF, Barker D, Wright E, Skolnick M, Kondoleon S, Litt M, Laouel J-M, et al. A mapped set of DNA markers for human chromosome 17. Genomics. 1988 May;2(4):302-309.

Hassold T, Benham F, Leppert MF Cytogenetic and molecular analysis of sex-chromosome monosomy. Am J Hum Genet. 1988 Apr;42(4):534-541.

Lathrop M, Nakamura Y, Cartwright P, O’Connell P, Leppert MF, Jones C, Tateishi H, Bragg T, Lalouel J-M, White R. A primary genetic map of markers of human chromosome 10. Genomics. 1988 Feb;2(2):157-164.

DeCroo S, Kamboh MI, Leppert M, Ferrell RE. Isoelectric focusing of superoxide dismutase: report of the unique SOD A*2 allele in a US white population. Hum Hered. 1988 38(1):1-7.

Lathrop M, Farrall M, O’Connell P, Wainwright B, Leppert MF, Nakamura Y, Lench N, Kruyer H, Dean M, Park M, Vande Woude G, Lalouel J-M, Williamson R, and White R. Refined linkage map of chromosome 7 in the region of the cystic fibrosis gene. Am J Hum Genet. 1988 Jan;42:38-44.

Leppert MF, Dobbs M, Scambler P, O’Connell P, Nakamura Y, Stauffer D, Woodward S, Burt R, Hughes J, Gardner E, Lathrop M, Wasmuth J, Lalouel J-M, and White R. The gene for familial polyposis coli maps to the long arm of chromosome 5. Science. 1987 Dec 4;238(4832):1411-1413.

White R, Nakamura Y, O’Connell P, Leppert MF, Lalouel J-M, Barker D, Goldgar D, Skolnick M, Carey J, Mathew C, Ponder B, Wallis C, and Slater C. Tightly linked markers for the neurofibromatosis type 1 gene. Genomics. 1987 Dec;1(4):364-367.

Hassold T, Jacobs PA, Leppert M, Sheldon M. Cytogenetic and molecular studies of trisomy 13. J Med Genet. 1987 Dec;24(12):725-732.

Scarpati EM, Sadler JE, O’Connell P, Nakamura Y, Leppert MF, Ballard L, Lathrop GM, Lalouel J-M, White R. Identification and mapping of RFLPs for human tissue factor (HTF) to chromosome 1p. Nucleic Acids Res. 1987 Nov 11;15(21):9098.

Keppen L, Leppert MF, O’Connell P, Nakamura Y, Stauffer D, Lathrop M, Lalouel J-M, and White R. Etiological heterogeneity in X-linked spastic paraplegia. Am J Hum Genet. 1987 Nov;41(5):933-943.

Page DC, Bieker K, Brown L, Hinton S, Leppert MF, Lalouel J-M, Lathrop M, Nystrom-Lahti M, de la Chapelle A, and White R. Linkage, physical mapping, and DNA sequence analysis of pseudoautosomal loci on the human X and Y chromosomes. Genomics. 1987 Nov;1(3):243-256.

Wainwright B, Tsui L-C, Leppert MF, Buchwald M, Estivill X, O’Connell P, Lathrop M, Lalouel J-M, White R, Williamson R, and Farrall M. Linkage of DNA Probe B79a (D7S13) to Cystic Fibrosis. Am J Hum Genet. 1987 Nov;41:944-947.

White R, Lalouel J-M, Leppert MF, Nakamura Y, and O’Connell P. Mapping Approaches to Gene Identification in Humans. West J Med. 1987 Oct;147(4):423-427.

Dean M, O’Connell P, Leppert MF, Park M, Amos J, Phillips D, White R, and Vande Woude G. Three additional DNA polymorphisms in the met gene and D7S8 locus: use in prenatal diagnosis of cystic fibrosis. J Pediatr. 1987 Oct;111(4):490-495.

O’Connell P, Lathrop M, Law M, Leppert MF, Nakamura Y, Hoff M, Kumlin E, Thomas W, Elsner T, Ballard L, Goodman P, Azen E, Sadler JE, Cai GY, Lalouel J-M, and White R. A Primary Genetic Linkage Map for Human Chromosome 12. Genomics. 1987 Sep;1(1):93-102.

White R, Leppert MF, O’Connell P, Nakamura Y, Holm T, Lathrop M, and Lalouel J-M. Linkage maps of human genes. Acta Paediatr Jpn. 1987 Aug;29(4):482-488.

Buroker NE, Bufton L, Surti U, Leppert M, Kumlin E, Sheehy R, Magenis RE and Litt M. A Hypervariable Region at the D19S11 Locus. Hum Genet. 1987 May;76(1):90-95.

Nakamura Y, Leppert MF, O’Connell P, Wolff R, Culver M, Martin C, Fujimoto E, Hoff M, Kumlin E, and White R. Variable number of tandem repeat (VNTR) markers for human gene mapping. Science. 1987 Mar 27;235(4796):1616-1622.

Nakamura Y, Julier C, Wolff R, Holm T, O’Connell P, Leppert MF, White R. Characterization of a human ‘midi satellite’ sequence. Nucleic Acids Res. 1987 Mar 25;15(6):2537-2547.

O’Connell P, Leppert MF, Nakamura Y, Dean M, Park M, Vande Woude G, Farrall M, Wainwright B, Williamson R, Lathrop GM, et al. DNA Markers for the cystic fibrosis locus. Prog Clin Biol Res. 1987 254:127-137.

White RL, Leppert MF, O’Connell P, Nakamura Y, Woodward S, Hoff M, Herbst J, Dean M, Vande Woude G, Lathrop M, and Lalouel J-M. Further linkage data on cystic fibrosis: The Utah Study. Am J Hum Genet. 1986 Dec;39(6):681-693.

Leppert MF, Cavanee W, Callahan P, Holm T, O’Connell P, Thompson K, Lathrop GM, Lalouel J-M, and White RL. A primary genetic map for chromosome 13q. Am J Hum Genet. 1986 Oct;39:425-437.

Leppert MF, Hasstedt S, Holm T, O’Connell P, Wu L, Ash O, Williams R, and White RL.
A DNA probe for the LDL receptor gene is tightly linked to hypercholesterolemia in a pedigree with early coronary disease. Am J Hum Genet. 1986 Sep;39(3):300-306.

White R, Leppert MF, O’Connell P, Nakamura Y, Julier C, Woodward S, Silva A, Wolff R, Lathrop M, and Lalouel J-M. Construction of human genetic linkage maps. I. Progress and perspectives. Cold Spring Harb Symp Quant Biol. 1986 51 Pt 1:29-38.

Surti U, Szulman AE, Wagner K, Leppert MF, and O’Brien SJ. Tetraploid partial hydatidiform moles: two cases with a triple paternal contribution and a 92, XXXY karyotype. Hum Genet. 1986 Jan;72(1):15-21.

White RL, Woodward S, Leppert MF, O’Connell P, Nakamura Y, Hoff M, Herbst J, Lalouel J-M, Dean M, and Vande Woude G. A closely linked genetic marker for cystic fibrosis. Nature. 1985 Nov 28 – Dec 4;318(6044):382-384.

Hassold T, Kumlin E, Leppert MF, Takaesu N. Determination of the parental origin of sex chromosome monosomy using restriction fragment length polymorphisms. Am J Hum Genet. 1985 Sep;37(5):965-972.

White R, Leppert M, Bishop DT, Barker D, Berkowitz J, Brown C, Callahan P, Holm T and Jerominski L. Construction of linkage maps with DNA markers for human chromosomes. Nature. 1985 Jan 10-18;313(5998):101-105.

Hassold T, Kumlin E, Takaesu N and Leppert MF. Use of restriction fragment length polymorphisms to study the origin of human aneuploidy. Ann N Y Acad Sci. 1985 450:179-189.

Blumberg BM, Leppert MF, and Kolakofsky D. Interaction of VSV leader RNA and nucleocapsid protein may control VSV genome replication. Cell. 1981 Mar;23(3):837-845.

Leppert MF and Kolakofsky D. Effect of defective interfering particles on plus- and minus- strand leader RNAs in vesicular stomatitis virus-infected cells. J Virol. 1980 Sep;35(3):704-709.

Leppert MF, Rittenhouse L, Perrault J, Summers DF, and Kolakofsky D. Plus and minus strand leader RNAs in negative strand virus-infected cells. Cell. 1979 Nov;18(3):735-747.

Leppert MF and Kolakofsky D. 5′ Terminus of defective and non-defective Sendai viral genomes is ppp Ap. J Virol. 1978 Jan;25(1):427-432.

Leppert M, Kort L, and Kolakofsky D. Further characterization of Sendai virus DI-RNAs: A model for their generation. Cell. 1977 Oct;12(2):539-552.

Schmid W and Leppert MF. Rates of DNA synthesis in heterochromatic and euchromatic segments of the chromosomes of two rodents. Cytogenetics. 1969 8(2):125-135.

Leppert MF. Chromosomal disorders of the unborn. Bull Am Coll Nurse Midwifery. 1968 May;13(2):14-17.

Schmid W and Leppert MF. Karotype, heterochromatin und DNS-werte bei 13 arten von wuhlmausen (Microtinae, Mammalia-Rodentia). Arch Julius Klaus Stift Verebungsforsch Sozialanthropol Rassenhyg. 1968 43(Suppl):81-91.

Schmid W and Leppert MF. Mammalian X-Chromosomes: A new kind of composite type X in the vole Arvicola scherman exitus Miller. Experientia. 1968 Mar 15;24(3):277-279.

 

 

 

 

 

Chapters

Leppert, M. 1999. Genetic research and the clinical subtleties of mental illness. In Genetics and Criminality; The Potential Misuse of Scientific Information in Court. (JR Botkin, WM McMahon and LP Francis, eds.) Washington, D.C:American Psychological Association, pp 106-108.

Leppert, M. The Genetics of Gastrointestinal Polyposis: 1993. Identification of the Adenomatous Polyposis Coli Gene. In Problems in General Surgery, Vol 10 Number 4. (AL Watne, LM Nyhus, eds.) Philadelphia:J.B. Lippincott Co.

Singh N, Charlier C, Peiffer A, Stauffer D, Melis R, Enoch MA, Goldman D, Rogers S, Anderson VE, Leppert, M. 1999. Genes for rare idiopathic generalized epilepsies: BFNC. In Advances in Neurology Series: Jasper’s Basic Mechanisms of the Epilepsies, Third Edition: (AV delgado-Escueta, WA Wilson, RW Olsen, and RJ Porter, eds.) New York:Lippincott-Raven Publishers, pp 341-350.

McMahon W, Leppert M, Filloux F, van de Wetering B and Hasstedt S. 1992. Tourette symptoms in 161 related family members. In Advances in Neurology, Vol 58, Tourette Syndrome: Genetics, Neurobiology, and Treatment (TN Chase, AJ Friedhoff and DJ Cohen, eds.) pp 159-65.

Leppert M, Anderson VE, and White R. 1991. The discovery of epilepsy genes by genetic linkage. In Genetic Strategies in Epilepsy Research; Epilepsy Research Supplement No.4, (VE Anderson, WA Hauser, IE Leppik, JL Noebels and SS Rich, eds.) pp 181-188.

Leppert M, and Lewis R. 1991. Human genetic mapping and inherited deafness syndromes. In Genetics of Hearing Impairment; Annals of the New York Academy of Sciences, (RJ Ruben, TR Van De Water and KP Steel,eds.) Vol 630, pp 38-48.

White R, Leppert M, Nakamura Y, O’Connell P, Lathrop M, Lalouel J-M. 1990. Mapping genes that cause disease. In The Cellular and Molecular Biology of Human Carcinogenesis. Proc. Briston-Myers Cancer Symposium #11 (RK Boutwell and IL Riegel, eds.) San Diego:Academic Press, pp. 61-77.

White R, Nakamura Y, O’Connell P, and Leppert M. 1990. Mapping genetic defects in linkage studies in families: A strategy for finding genes associated with cancer syndromes. In Genetic Mechanisms in Carcinogenesis and tumor progression. UCLA Symp. Molec. & Cellular Biol., New Series, Vol. 114. New York:Wiley-Liss, pp 153-161.

Leppert M and Ward K. 1990. Automated DNA screening: the problems and the possibilities. 1990. In Genetic Screening from Newborns to DNA typing, Proc. of the “Workshop on Genetic Screening” Oct 1989, La Sapiniere, Quebec, Canada. (BM Knoppers and CM Laberge, eds.) pp 151-157, and 295, 333, 357.

Leppert M; Nakamura Y; Burt R; Hughes JP, Samowitz W, Woodward S, Gardner E, Lalouel, J-M and White, R. 1990. Eldon Gardner Memorial Lecture: Genetic mapping and allelic heterogeneity of the familial polyposis gene. In Hereditary Colorectal Cancer, Proc. of the “4th International Symposium on Colorectal Cancer” Nov 1989, Kobe, Japan. (J Utsunomiya and HT Lynch, eds.) pp 27-36.

White R, Leppert M, Nakamura Y, O’Connell P, Lathrop M, and Lalouel J-M. 1990. Mapping genes that cause disease. In Procedures of. Bristol-Myers Cancer Symposium #11, (R.K. Boutwell and I.L. Riegel, eds.), San Diego: Academy Press, pp 61-77.

O’Connell P, Lathrop M, Leppert M, Nakamura Y, Dean M, Park M, Vande Woude G, Farrall M, Wainwright B, Williamson R, Lalouel J-M, and White R. 1988. Linkage mapping studies in the region of cystic fibrosis. In Cellular and Molecular Basis of Cystic Fibrosis (Mastella, G. and Quinton, P.M., eds.) San Francisco:San Francisco Press, pp 51-59.

Leppert M, O’Connell P, Sears T, Park M, Dean M, Vande Woude G, Lathrop M, and White R. 1988. DNA probes in the cystic fibrosis region of chromosome 7. In Nucleic Acid Probes in Human Genetic Disease. (Willey, A., ed.) New York:Allan R. Liss.

O’Connell P, Leppert M, Nakamura Y, Dean M, Park M, Vande Woude G, Farrall M, Wainwright B, Williamson R, Lathrop M, Lalouel J-M, and White R. 1987. DNA markers for the cystic fibrosis locus. In Genetics and Epithelial Cell Dysfunction in Cystic Fibrosis (Riordan, J.R. and Buchwald, M. eds.) New York:Alan R. Liss, pp 127-137.

White RL, Nakamura Y, Julier C, Silva A, O’Connell P, Leppert M, Lathrop M, and Lalouel J-M. 1986. Linkage maps of human chromosomes. In DNA Probes: Applications in Genetic and Infectious Disease and Cancer. Cold Spring Harbor Laboratory Current Commun. mole. Biol. (L.S. Lerman, ed.), New York:Cold Spring Harbor, pp 43-47.

Hassold, T; Kumlin, E; Takaesu, N; Leppert, M. 1985. Use of Restriction Fragment Length Polymorphisms to Study the Origin of Human Aneuploidy. In Molecular Structure of the Number 21 Chromosome and Down Syndrome; Annals of the New York Academy of Sciences, (G.F Smith, editor.) Vol 450, pp 179-89.

White RL, Leppert M, Drayna D, Leach R, and Barker D. Human Genetic Linkage Studies with DNA Markers. 1984. In Advances in Gene Technology: Human Genetic Disorders. Proceedings of the 16th Miami Winter Symposium, Fazal Ahman, et al. eds. ICSU Short Reports I:86-89.

White R, Leppert M, Bishop DT, Barker D, Berkowitz J, Brown C, Callahan P, Holm T, and Jerominski L. 1984. High Resolution Linkage Map of Human Chromosome 11p. In Chromosomes Today, vol. VIII, pgs. 23-32, M.D. Bennett, A. Gropp and U. Wolf, eds. London:George Allen & Unwin.

White R, Barker D, Cavanee W, Leach R, Drayna D, Holm T, Berkowitz J, and Leppert M. 1983. Approaches to Human Genetics Based on DNA Sequence Polymorphism. In Recombinant DNA and Medical Genetics, eds. H. Harris and K.H. Hirschhorn. New York:Academic Press, pp 73-77.

White R, Barker D, Holm T, Berkowitz J, Leppert M, Cavanee W, Leach R, and Drayna D. 1983. Approaches to Linkage Analysis in the Human. In Banbury Report 14: Recombinant DNA Applications to Human Disease, eds. C.T. Caskey and R.L. White. New York:Cold Spring Harbor.

Kolakofsky D, Leppert MF, and Kort L. 1978. A Genetic Map of Sendai Virus DI RNAs. In Negative Strand Viruses and the Host Cell, eds. R. Barry and B. Mahey. London:Academic Press, pp. 539-553.

 

 

 

 

Other Publications

Samowitz WS, Burt RW, and Leppert MF. Gastrointestinal polyposis and nonpolyposis syndromes N Engl J Med. 1995 332:1518.

Borish L, Mascali JJ, Klinnert M, Leppert MF, and Rosenwasser LJ. SSC polymorphisms in interleukin genes. Hum Mol Genet. 1995 3:1710.

Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R.Isolation and mapping of a polymorphic DNA sequence pEFD64.1 on chromosome 3. Nucleic Acids Res. 1988 Nov 25;16(22):10947.

Fujimoto E, Nakamura Y, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFZ33 on chromosome 15. Nucleic Acids Res. 1988 Nov 25;16(22):10946.

Holm T, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH55 on chromosome. Nucleic Acids Res. 1988 Nov 25;16(22):10945.

Fujimoto E, Nakamura Y, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD49.3 on chromosome 15. Nucleic Acids Res. 1988 Nov 25;16(22):10944.

Fujimoto E, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD49.2 on chromosome 15. Nucleic Acids Res. 1988 Nov 25;16(22):10943.

Fujimoto E, Nakamura Y, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD52.1 on chromosome 15. Nucleic Acids Res. 1988 Nov 25;16(22):10942.

Carlson M, Nakamura Y, Krapcho K, Payson R, O’Connell P, Leppert M, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT149.2 on chromosome 15. Nucleic Acids Res. 1988 Nov 25;16(22):10941.

Nakamura Y, Hoff M, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMHZ21 on chromosome 9q (D9S30). Nucleic Acids Res. 1988 Nov 11;16(21):10409.

Nakamura Y, Krapcho K, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pKKA40 on chromosome 9q (D9S31). Nucleic Acids Res. 1988 Nov 11;16(21):10408.

Nakamura Y, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHBI59 on chromosome 11 (D11S146). Nucleic Acids Res. 1988 Nov 11;16(21):10404.

Nakamura Y, Krapcho K, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNH20 on chromosome 13 (D13S50). Nucleic Acids Res. 1988 Nov 11;16(21):10402.

Hoff M, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMHZ17 on chromosome 13 (D13S51). Nucleic Acids Res. 1988 Nov 11;16(21):10401.

Hoff M, Nakamura Y, Holm T, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH208 on chromosome 14 (D14S19). Nucleic Acids Res. 1988 Nov 11;16(21):10400.

Nakamura Y, Culver M, Leppert MF, Sergeant L, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ132 on chromosome 6 (D6S40). Nucleic Acids Res. 1988 Oct 25;16(20):9889.

Nakamura Y, Fujimoto E, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD6 on chromosome 6 (D6S41). Nucleic Acids Res. 1988 Oct 25;16(20):9888.

Holm T, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH28 on chromosome 7p (D7S371). Nucleic Acids Res. 1988 Oct 25;16(20):9887.

Nakamura Y, Krapcho K, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pKKA12 on chromosome 7 (D7S398). Nucleic Acids Res. 1988 Oct 25;16(20):9886.

Wolff E, Nakamura Y, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEKMDA2-I on chromosome 16 (D16S83). Nucleic Acids Res. 1988 Oct 25;16(20):9885.

Nakamura Y, Culver M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ94 on chromosome 17 (D17S80). Nucleic Acids Res. 1988 Oct 25;16(20):9884.

Myers R, Nakamura Y, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pRMR6 on chromosome 20 (D20S20). Nucleic Acids Res. 1988 Oct 25;16(20):9883.

Nakamura Y, Carlson M, Krapcho K, Ballard L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT15 on chromosome 21 (D21S113). Nucleic Acids Res. 1988 Oct 25;16(20):9882.

Nakamura Y, Carlson M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT96.1 and pMCT96.2 on chromosome 9q (D9S14). Nucleic Acids Res. 1988 Oct 25;16(20):9881.

Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence cYNA4 on chromosome 2 (D2S50). Nucleic Acids Res. 1988 Oct 11;16(19):9362.

Nakamura Y, Martin C, Krapcho K, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM63 on chromosome 2 (D2S51). Nucleic Acids Res. 1988 Oct 11;16(19):9361.

Krapcho K, Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFZ38 on chromosome 2 (D2S60). Nucleic Acids Res. 1988 Oct 11;16(19):9360.

Nakamura Y, Carlson M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT106 on chromosome 2 (D2S61). Nucleic Acids Res. 1988 Oct 11;16(19):9359.

Carlson M, Nakamura Y, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT32.1 on chromosome 3 (D3S31). Nucleic Acids Res. 1988 Oct 11;16(19):9358.

Fujimoto E, Nakamura Y, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD145 on chromosome 3 (D3S32). Nucleic Acids Res. 1988 Oct 11;16(19):9357.

Nakamura Y, Carlson M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCOD13 on chromosome 3 (D3S44). Nucleic Acids Res. 1988 Oct 11;16(19):9356.

Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD134.7 on chromosome 3 (D3S45). Nucleic Acids Res. 1988 Oct 11;16(19):9355.

Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD64.2 on chromosome 3 (D3S46). Nucleic Acids Res. 1988 Oct 11;16(19):9354.

Nakamura Y, Carlson M, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCOE32 on chromosome 2 (D2S53). Nucleic Acids Res. 1988 Jul 11;16(13):6258.

Nakamura Y, Carlson M, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCOC12 on chromosome 14 (D14S20). Nucleic Acids Res. 1988 Jul 11;16(13):6257.

Fujimoto E, Nakamura Y, Kanamori M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD85.7 on chromosome 15 (D15S37). Nucleic Acids Res. 1988 Jul;16:6256.

Nakamura Y, Martin C, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM66 on chromosome 14 (D14S22). Nucleic Acids Res. 1988 Jul 11;16(13):6255.

Nakamura Y, Carlson M, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCOC14 on chromosome 4p (D4S124). Nucleic Acids Res. 1988 Jul 11;16(13):6254.

Holm T, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH28 on chromosome 7p (D7S371). Nucleic Acids Res. 1988 Jun 24;16(12):5709.

Nakamura Y, Culver M, Leppert M, Sergeant L, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ132 on chromosome 6 (D6S40). Nucleic Acids Res. 1988 Jun 24;16(12):5708

Nakamura Y, Ballard L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ22 on chromosome 17p (D17S30). Nucleic Acids Res. 1988 Jun 24;16(12):5707.

Nakamura Y, Krapcho K, Ballard L, Leppert M, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pKKA35 on chromosome 17 (D17S75). Nucleic Acids Res. 1988 Jun 24;16(12):5706.

Nakamura Y, Ballard L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNH3 on chromosome X (DXS287). Nucleic Acids Res. 1988 Jun 24;16(12):5705.

Krapcho K, Nakamura Y, Fujimoto E, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFZ13 on chromosome 1p (D1S64). Nucleic Acids Res. 1988 Jun 24;16(12):5704.

Nakamura Y, Hoff M, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMHZ13 on chromosome 9 (D9S13). Nucleic Acids Res. 1988 Jun 24;16(12):5703.

Nakamura Y, Culver M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ15 on chromosome 2 (D2S50). Nucleic Acids Res. 1988 Jun 24;16(12):5702.

Holm T, Nakamura Y, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHIZ53 on chromosome 12 (D12S18). Nucleic Acids Res. 1988 Jun 24;16(12):5701.

Nakamura Y, Martin C, Myers R, Ballard L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM86 on chromosome 17q (D17S74). Nucleic Acids Res. 1988 Jun 10;16(11):5223.

Nakamura Y, Martin C, Leppert M, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM6 on chromosome 20 (D20S19). Nucleic Acids Res. 1988 Jun 10;16(11):5222.

Krapcho K, Nakamura Y, Fujimoto E, Eldridge R, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFZ31 on chromosome 22 (D22S32). Nucleic Acids Res. 1988 Jun 10;16(11):5221.

Martin C, Nakamura Y, Myers R, Ballard L, O’Connell PO, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM62 on chromosome 14 (D14S21). Nucleic Acids Res. 1988 Jun 10;16(11):5220.

Nakamura Y, Martin C, Krapcho K, Ballard L, O’Connell PO, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMI40 on chromosome 13 (D13S49). Nucleic Acids Res. 1988 Jun 10;16(11):5219.

Nakamura Y, Holm T, Hoff M, Gillilan S, Leppert MF, O’Connell PO, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH106 on chromosome 1 (D1S67). Nucleic Acids Res. 1988 Jun 10;16(11):5218.

Hoff M, Nakamura Y, Holm T, Gillilan S, O’Connell PO, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH157 on chromosome 6p (D6S29). Nucleic Acids Res. 1988 Jun 10;16(11):5217.

Holm T, Nakamura Y, Ballard L, O’Connell PO, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH22 on chromosome 9 (D9S12). Nucleic Acids Res. 1988 Jun 10;16(11):5216.

Fujimoto E, Nakamura Y, Payson R, O’Connell P, Leppert MF, Lathrop GM, Leppert J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD70.3 on chromosome 18 (D18S23). Nucleic Acids Res. 1988 May 25;16(10):4748.

Nakamura Y, Culver M, Sergeant L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ2 on chromosome 1p1 (D1S57). Nucleic Acids Res. 1988 May 25;16(10):4747.

Holm T, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH26 on chromosome 11 (D11S149). Nucleic Acids Res. 1988 May 25;16(10):4746.

Carlson M, Nakamura Y, Krapcho K, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence MCT117 on chromosome 11 (D11S145). Nucleic Acids Res. 1988 May 25;16(10):4745.

Carlson M, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCOA12 on chromosome 9q (D9S28). Nucleic Acids Res. 1988 May 25;16(10):4744.

Nakamura Y, Cowen J, Martin C, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pJCZ30 on chromosome 6 (D6S37). Nucleic Acids Res. 1988 May 25;16(10):4743.

Hoff M, Nakamura Y, Holm T, Payson R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH171 on chromosome 6p (D6S38). Nucleic Acids Res. 1988 May 25;16(10):4742.

Hoff M, Nakamura Y, Holm T, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH119 on chromosome 1 (D1S59). Nucleic Acids Res. 1988 May 25;16(10):4741.

Nakamura Y, Martin C, Silva A, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMI37 on chromosome 7 (D7S368). Nucleic Acids Res. 1988 May 11;16(9):4192.

Nakamura Y, Cowen J, Myers R, Ballard L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pJCZ7 on chromosome 7 (D7S396). Nucleic Acids Res. 1988 May 11;16(9):4191.

Martin C, Nakamura Y, Myers R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM17.4 on chromosome 10 (D10S23). Nucleic Acids Res. 1988 May 11;16(9):4190.

Hoff M, Nakamura Y, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH163 on chromosome 18 (D18S21). Nucleic Acids Res. 1988 May 11;16(9):4189.

Carlson M, Nakamura Y, Payson R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT108.2 on chromosome 18 (D18S24). Nucleic Acids Res. 1988 May 11;16(9):4188.

Nakamura Y, Bragg T, Myers R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTB10.171 on chromosome 10 (D10S19). Nucleic Acids Res. 1988 May 11;16(9):4187.

Nakamura Y, Culver M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ32 on chromosome 4p (D4S125). Nucleic Acids Res. 1988 May 11;16(9):4186.

Bragg T, Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTB10.163 on chromosome 10 (D10S22). Nucleic Acids Res. 1988 May 11;16(9):4185.
Nakamura Y, Holm T, Gillilan S, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH59 on chromosome 17q (D17S4). Nucleic Acids Res. 1988 Apr 25;16(8):3598.

Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence cYNA12 on chromosome 13 (D13S53). Nucleic Acids Res. 1988 Apr 25;16(8):3597.

Martin C, Nakamura Y, Hoff M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM1.2 on chromosome 12q (D12S15).| Nucleic Acids Res. 1988 Apr 25;16(8):3596.

Nakamura Y, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNA15.2 on chromosome 15 (D15S36). Nucleic Acids Res. 1988 Apr 25;16(8):3595.

Nakamura Y, Carlson M, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence cMCOC46 on chromosome 13 (D13S54). Nucleic Acids Res. 1988 Apr 25;16(8):3594.

Nakamura Y, Ballard L, Holm T, O’Connell P, Leppert M, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH37 on chromosome 14 (D14S16). Nucleic Acids Res. 1988 Apr 25;16(8):3593.

Nakamura Y, Martin C, Myers R, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNM18.1 on chromosome 15 (D15S35). Nucleic Acids Res. 1988 Apr 25;16(8):3592.

Myers R, Nakamura Y, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pRMU7.4 on chromosome 7p (D7S370). Nucleic Acids Res. 1988 Apr 25;16(8):3591.

Nakamura Y, Carlson M, Krapcho K, Ballard L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT128.2 on chromosome 8 (D8S39). Nucleic Acids Res. 1988 Apr 25;16(8):3590.

Nakamura Y, Martin C, Krapcho K, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM65 on chromosome 16 (D16S84). Nucleic Acids Res. 1988 Apr 11;16(7):3122.

Martin C, Nakamura Y, Myers R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pCMM17.1 on chromosome 10 (D10S16). Nucleic Acids Res. 1988 Apr 11;16(7):3121.

Nakamura Y, Krapcho K, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence cKKA39 on chromosome 14 (D14S23). Nucleic Acids Res. 1988 Apr 11;16(7):3120.

Nakamura Y, Hoff M, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence cMHZ47 on chromosome 13 (D13S52). Nucleic Acids Res. 1988 Apr 11;16(7):3119.

Holm T, Nakamura Y, Hoff M, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH14 on chromosome 12p (D12S16). Nucleic Acids Res. 1988 Apr 11;16(7):3118.

Holm T, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH55 on chromosome 15 (D15S27). Nucleic Acids Res. 1988 Apr 11;16(7):3117.

Fujimoto E, Nakamura Y, Martin C, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD53.2 on chromosome 1 (D1S73). Nucleic Acids Res. 1988 Apr 11;16(7):3116.

Holm T, Nakamura Y, Ballard L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHI54 on chromosome 1p (D1S62). Nucleic Acids Res. 1988 Apr 11;16(7):3115.

Nakamura Y, Cowen J, Krapcho K, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R.Isolation and mapping of a polymorphic DNA sequence pJCZ3.1 on chromosome 19 (D19S20). Nucleic Acids Res. 1988 Feb 11;16(3):1229.

Nakamura Y, Fujimoto E, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD4.2 on chromosome 19 (D19S22). Nucleic Acids Res. 1988 Feb 11;16(3):1228

Krapcho K, Nakamura Y, Fujimoto E, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFZ10 on chromosome 18 (D18S22). Nucleic Acids Res. 1988 Feb 11;16(3):1227.

Carlson M, Nakamura Y, Krapcho K, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT46.2 on chromosome 15 (D15S26). Nucleic Acids Res. 1988 Feb 11;16(3):1226.

Carlson M, Nakamura Y, Sargeant L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCA1-1 on chromosome 15 (D15S33). Nucleic Acids Res. 1988 Feb 11;16(3):1225.

Kumlin-Wolff E, Nakamura Y, Myers R, Eldridge JR, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEKZ104.1 on chromosome 15 (D15S30). Nucleic Acids Res. 1988 Feb 11;16(3):1224.

Hoff M, Nakamura Y, Holm T, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH152 on chromosome 17q (D17S32). Nucleic Acids Res. 1988 Jan 25;16(2):787.

Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence cEFD52 on chromosome 17q (D17S26). Nucleic Acids Res. 1988 Jan 25;16(2):786.

Myers R, Nakamura Y, Gillilan S, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pRMU1 on chromosome 17q (D17S27). Nucleic Acids Res. 1988 Jan 25;16(2):785.

Myers R, Nakamura Y, Ballard L, Leppet MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pRMU3 on chromosome 17q (D17S24). Nucleic Acids Res. 1988 Jan 25;16(2):784.

Carlson M, Nakamura Y, Payson R, O’Connell P, Leppert M, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT35.1 on chromosome 17p (D17S31). Nucleic Acids Res. 1988 Jan 25;16(2):783.

Nakamura Y, Bragg T, Ballard L, Leppert MF, O’Connell P, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNH37.3 on chromosome 17p (D17S28). Nucleic Acids Res. 1988 Jan 25;16(2):782.

Hoff M, Nakamura Y, Holm T, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH202 on chromosome 17 (D17S33). Nucleic Acids Res. 1988 Jan 25;16(2):781.

Nakamura Y, Culver M, Krapcho K, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ90.1 on chromosome 15 (D15S28). Nucleic Acids Res. 1988 Jan 25;16(2):780.

Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNH15 on chromosome 12q (D12S17). Nucleic Acids Res. 1988 Jan 25;16(2):779.

Nakamura Y, Fujimoto E, Martin C, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD33.2 on chromosome 12 (D12S14). Nucleic Acids Res. 1988 Jan 25;16(2):778.

Nakamura Y, Culver M, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMLJ14 on chromosome 14 (D14S13). Nucleic Acids Res. 1988 Jan 11;16(1):381.

Fujimoto E, Nakamura Y, Payson R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFZ18.2 on chromosome 14 (D14S17). Nucleic Acids Res. 1988 Jan 11;16(1):380.

Nakamura Y, Hoff M, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMHZ29 on chromosome 14 (D14S18). Nucleic Acids Res. 1988 Jan 11;16(1):379.

Carlson M, Nakamura Y, Krapcho K, Payson R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence MCT128.1 on chromosome 11 (D11S285). Nucleic Acids Res. 1988 Jan 11;16(1):378.

Nakamura Y, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHBI18P2 on chromosome 11 (D11S147). Nucleic Acids Res. 1988 Jan 11;16(1):377.

Nakamura Y, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHBI59 on chromosome 11 (D11S146). Nucleic Acids Res. 1988 Jan 11;16(1):376.

Nakamura Y, Culver M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ156 on chromosome 10 (D10S18). Nucleic Acids Res. 1988 Jan 11;16(1):375.

Nakamura Y, Carlson M, Krapcho K, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCK2 on chromosome 10 (D10S15). Nucleic Acids Res. 1988 Jan 11;16(1):374.

Hoff M, Nakamura Y, Payson R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMHZ15 on chromosome 10 (D10S17). Nucleic Acids Res. 1988 Jan 11;16(1):373.

Holm T, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTHH54 on chromosome 10q (D10S13). Nucleic Acids Res. 1988 Jan 11;16(1):372.

Carlson M, Nakamura Y, Krapcho K, Fujimoto E, O’Connell P, Leppert M, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT112 on chromosome 9q (D9S15). Nucleic Acids Res. 1987 Dec10;15(24):10614.

Carlson M, Nakamura Y, Krapcho K, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMCT136 on chromosome 9q (D9S10). Nucleic Acids Res. 1987 Dec 10;15(24):10613.

Fujimoto E, Nakamura Y, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD40.3 on chromosome 9q (D9S8). Nucleic Acids Res. 1987 Dec 10;15(24):10612.

Kumlin-Wolff E, Nakamura Y, Myers R, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEKZ19.3 on chromosome 9q (D9S17). Nucleic Acids Res. 1987 Dec 10;15(24):10611.

Nakamura Y, Hoff M, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMHZ10 on chromosome 9q (D9S11). Nucleic Acids Res. 1987 Dec 10;15(24):10609.

Nakamura Y, Martin C, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNM17 on chromosome 9q (D9S6). Nucleic Acids Res. 1987 Dec 10;15(24):10608.

Nakamura Y, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of apolymorphic DNA sequence pEFD126.3 on chromosome 9q (D9S7). Nucleic Acids Res. 1987 Dec 10;15(24):10607.

Hoff M, Nakamura Y, Holm T, Payson R, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH220 on chromosome 9p (D9S27). Nucleic Acids Res. 1987 Dec 10;15(24):10606.

Nakamura Y, Martin C, Leppert M, O’Connell P, Lathrop GM, Lalouel J-M, White, R. Isolation and mapping of a polymorphic DNA sequence pYNM3 on chromosome 8 (D8S38). Nucleic Acids Res. 1987 Dec 10;15(23):10080.

Nakamura Y, Culver M, Gillilan S, O’Connell P, Leppert M, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ86.1 on chromosome 3 (D3S30). Nucleic Acids Res. 1987 Dec 10;15(23):10079.

Fujimoto E, Nakamura Y, O’Connell P, Leppert M, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEFD122 on chromosome 2 (D2S48). Nucleic Acids Res. 1987 Dec 10;15(23):10078.

Hoff M, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH115.2 on chromosome 2 (D2S54). Nucleic Acids Res. 1987 Dec 10;15(23):10077.

Kumlin-Wolff E, Nakamura Y, Krapcho K, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEKZ105 on chromosome 2 (D2S55). Nucleic Acids Res. 1987 Dec 10;15(23):10076.

Hoff M, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pHHH133 on chromosome 2 (D2S45). Nucleic Acids Res. 1987 Dec 10;15(23):10075.

Culver M, Nakamura Y, Ballard L, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ9.1 on chromosome 2 (D2S46). Nucleic Acids Res. 1987 Dec 10;15(23):10074.

Nakamura Y, Gillilan S, O’Connell P, Leppert M, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNH24 on chromosome 2 (D2S44). Nucleic Acids Res. 1987 Dec 10;15(23):10073.

Bragg T, Nakamura Y, Gill J, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pTBAB5.7 on chromosome 2 (D2S47). Nucleic Acids Res. 1987 Dec 10;15(23):10072.

Carlson M, Nakamura Y, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence for NRAS pMCR3 on chromosome 1. Nucleic Acids Res. 1987 Nov 25;15(22):9623.

Nakamura Y, Krapcho K, Fujimoto E, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of polymorphic DNA sequence pHBI40 on chromosome 1. Nucleic Acids Res. 1987 Nov 25;15(22):9622.

Kumlin-Wolff E, Nakamura Y, Hoff M, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pEKH7.4 to chromosome 1 (D1S65). Nucleic Acids Res. 1987 Nov 25;15(22):9621.

Nakamura Y, Culver M, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pYNZ23 to chromosome 1. Nucleic Acids Res. 1987 Nov 25;15(22):9620.

Hoff M, Nakamura Y, Gillilan S, O’Connell P, Leppert MF, Lathrop GM, Lalouel J-M, White R. Isolation and mapping of a polymorphic DNA sequence pMHZ14 on chromosome 1p. Nucleic Acids Res. 1987 Nov 25;15(22):9619.

Principal Investigator

null

Mark Leppert, Ph.D.

Distinguished Professor

Research Associates

Nori Matsunami

Research Associate

Phone: 1-6421

Jeff Stevens

Research Associate

Phone: 1-6421

Address

University of Utah
Eccles Institute of Human Genetics
15 N. 2030 E., Rm 7160
Salt Lake City, UT 84112-5330

Phone

801-581-8131

Fax

801-581-7404