School of Medicine
Seminar Series 2002-03

October 8
Sir John Skehel
Director, National Institute for Medical Research
Mill Hill, London, England
“How Viruses Enter Cells”
Host: Dana Carroll, Biochemistry

October 22
Tom Silhavy, Ph.D.
Department of Molecular Biology
Princeton University
“Sensing and Responding to Envelope Stress”
Host: Matt Mulvey, Pathology

October 29
Paul Meltzer, M.D. , Ph.D.
Section Head of Molecular Genetics, Cancer Genetics Branch
National Human Genome Research Institute
National Institutes of Health
“Using Genomics to Understand Cancer: Lessons from Microarray Research”
Host: David Virshup, Oncological Sciences

November 19
Ken Irvine, Ph.D.
Assistant Investigator/Associate Professor,
Howard Hughes Medical Institute/Rutgers University
“Regulation of Notch Signaling by Glycosylation”
Host: Carl Thummel, Human Genetics

December 3
Paul W. Kincade, Ph.D.
Immunobiology Program Head
Oklahoma Medical Research Foundation
“Characteristics of the Earliest Lymphocyte Progenitors in Fetal and Adult Life”
Host: Raymond A. Daynes, Pathology

January 7
Daniel L. Simmons, Ph.D.
Director, Chemistry and Biochemistry
Brigham Young University
“Potential Role of Cyclooxygenase Variants in Pharmacology”
Host: Tom McIntyre, Department of Medicine

January 14
Mark R. O’Brian, Ph.D.
Professor, Department of Biochemistry
State University of New York, Buffalo
“Heme Signaling in Bacteria”
Host: Pediatrics

January 28
Hans R. Scholer, Ph.D.
Professor, University of Pennsylvania, School of Veterans Medical
“Gene Function and Regulation in Embryonic Stem and Germ Cells”
Host: Eli Y. Adashi, M.D., Obstetrics and Gynecology

February 4
Michael B. O’Connor, Ph.D.
Professor and Associate Investigator
Department of Genetics Cell Biology and Development
Howard Hughes Medical Institute/University of Minnesota, Minneapolis
“TGF-Beta Signaling and Regulation of Synapse Development in Drosophila”
Host: Anthea Letsou, Human Genetics

February 11
Joseph Nevins, Ph.D.
Department of Molecular Genetics and Microbiology
Howard Hughes Medical Institute/Duke University Medical Center
“Gene Regulatory Networks Controlling Cell Growth and Oncogenesis”
Host: Don Ayer, Oncological Sciences

February 25
Edward K. Wakeland, Ph.D.
Professor and Director, Center of Immunology
University of Texas, Southwestern Medical Center, Dallas
“Delineating Genetic Pathways that Mediate Systemic Autoimmunity”
Host: Wayne Potts, Department of Biology

February 27 (Thursday)
C. Ronald Kahn, M.D.
President and Director, Joslin Diabetes Center
“Genetic Analysis of Insulin Regulation of Gene Expression”
Host: Guy Zimmerman, Human Molecular Biology and Genetics

March 4
Dennis J. Thiele, Ph.D.
Professor, Biological Chemistry
University of Michigan Medical School
“The Role of Copper in Growth and Development: Studies in Yeast, Flies and Mice”
Host: Dennis R. Winge, Hematology

March 18
Joseph G. Sodroski, M.D.
Professor of Pathology
Dana-Farber Cancer Institute
Harvard Medical School
“Early Events in Human Immunodeficiency Virus (HIV-1) Infection”
Host: Wes Sundquist, Biochemistry

March 25
Kevin P. Campbell, Ph.D.
Professor of Physiology
University of Iowa, College of Medicine
“Molecular Insights into the Pathogenesis of Congenital Muscular Dystrophy”
Host: James Bale, Pediatric Neurology

April 8
David A. Low, Ph.D.
Professor of Genetics
Department of Molecular, Cellular and Developmental Biology
University of California, Santa Barbara
“Molecular Analysis of Epigenetic Switches Controlling Pili Expression in Uropathogenic E. coli”
Host: Raymond A. Daynes, Pathology

April 22
Stephen J. Tapscott, M.D., Ph.D.
Division of Human Biology
Fred Hutchinson Cancer Research Center
“MyoD and the Regulation of Gene Expression in Normal Development and Disease”
Host: Susan Mango, Oncological Sciences

April 29
J. Lindsay Whitton, M.D., Ph.D.
Professor, Department of Neuropharmacology
Scripps Research Institute
“Antiviral CD8+ T Cell Responses: Regulation of Immunodominance and Effector Function”
Host: Robert S. Fujinami, Neurology and Pathology

May 6
Timothy Bestor, Ph.D.
Professor of Genetics and Development
College of Physicians and Surgeons of Columbia University
“Biology of Genomic Methylation Patterns”
Host: Glenn Herrick, Pathology

May 13
Kenneth Zaret, Ph.D.
Senior Member and Program Leader
Cell and Developmental Biology Program
Fox Chase Cancer Center
“Opening Chromatin in Early Development”
Host: Barbara Graves, Oncological Sciences

May 20
Jeffery W. Kelly, Ph.D.
Lita Annenberg Hazen Professor of Chemistry
Scripps Research Institute
“To Be Announced”
Host: Chris Hill, Biochemistry